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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q924Z4 Cers2 Ceramide synthase 2 (CerS2) (LAG1 … Mus musculus (Mouse) 380 aa

Protein Details: Q924Z4 (Cers2)

Protein Information
AccessionQ924Z4
Protein NamesCeramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297)
Gene SymbolCers2
OrganismMus musculus (Mouse)
Length380 aa
IsoformsNo isoforms
Related PMIDs 29217618 34884899 35477839 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLQTLYDYFW11WERLWLPVNL21TWADLEDKDG31RVYAKASDLY41ITLPLALLFL
51-10051VIRYFFELYV61ATPLAALLNV71KEKTRLRAPP81NATLEHFYQT91SGKQPKQVEV
101-150101DLLSRQSGLS111GRQVERWFRR121RRNQDRPSLL131KKFREASWRF141TYYLIAFVAG
151-200151MAVTVDKPWF161YDLRKVWEGY171PIQSIIPSQY181WYYMIELSFY191WSLLFSIASD
201-250201VKRKDFKEQI211IHHVATIILL221CFSWFANYVR231AGTLIMALHD241ASDYLLESAK
251-300251MFNYAGWKNT261CNNLFIVFAI271VFIITRLVIM281PFWILHCTMI291YPLELYPAFF
301-350301GYYFFNFMMA311VLQMLHIFWA321YFILRMAHKF331ITGKLIEDER341SDREETESSE
351-380351GEETAAGAGA361KSRLLANGHP371ILNNNHPKND
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
221 - - -
Deep-Palm: 0.07
261 - - -
Deep-Palm: 0.05
287 - - -
Deep-Palm: 0.12
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.625
5/5 (100.0%)
2
Testis
Specificity: 0.250
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine