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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q92506 HSD17B8; FABGL; HKE6; RING2; SDR30C1 (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid … Homo sapiens (Human) 261 aa

Protein Details: Q92506 (HSD17B8)

Protein Information
Accession Q92506
Protein Names (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239)
Gene Symbol HSD17B8; FABGL; HKE6; RING2; SDR30C1
Organism Homo sapiens (Human)
Length 261 aa
Isoforms No isoforms
Related PMIDs 31251020 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.964
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
27
LNCaP cells
Specificity: 0.964
27/46 (58.7%)
1
Cerebral cortex
Specificity: 0.036
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASQLQNRLR11SALALVTGAG21SGIGRAVSVR31LAGEGATVAA41CDLDRAAAQE
51-10051TVRLLGGPGS61KEGPPRGNHA71AFQADVSEAR81AARCLLEQVQ91ACFSRPPSVV
101-150101VSCAGITQDE111FLLHMSEDDW121DKVIAVNLKG131TFLVTQAAAQ141ALVSNGCRGS
151-200151IINISSIVGK161VGNVGQTNYA171ASKAGVIGLT181QTAARELGRH191GIRCNSVLPG
201-250201FIATPMTQKV211PQKVVDKITE221MIPMGHLGDP231EDVADVVAFL241ASEDSGYITG
251-261251TSVEVTGGLF261M
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
41 Prediction (High) - -
92 Prediction (Medium) - -
147 Prediction (Medium) - -
194 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
94 S → C 0.002427 SNP Missense Mutation BLCA
169 Y → Cfs*26 0.001969 DEL Frame Shift Del HNSC