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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q92688 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 … Homo sapiens (Human) 251 aa

Protein Details: Q92688 (ANP32B)

Protein Information
AccessionQ92688
Protein NamesAcidic leucine-rich nuclear phosphoprotein 32 family member B (Acidic protein rich in leucines) (Putative HLA-DR-associated protein I-2) (PHAPI2) (Silver-stainable protein SSP29)
Gene SymbolANP32B
OrganismHomo sapiens (Human)
Length251 aa
IsoformsNo isoforms
Related PMIDs 29733200
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDMKRRIHLE11LRNRTPAAVR21ELVLDNCKSN31DGKIEGLTAE41FVNLEFLSLI
51-10051NVGLISVSNL61PKLPKLKKLE71LSENRIFGGL81DMLAEKLPNL91THLNLSGNKL
101-150101KDISTLEPLK111KLECLKSLDL121FNCEVTNLND131YRESVFKLLP141QLTYLDGYDR
151-200151EDQEAPDSDA161EVDGVDEEEE171DEEGEDEEDE181DDEDGEEEEF191DEEDDEDEDV
201-250201EGDEDDDEVS211EEEEEFGLDE221EDEDEDEDEE231EEEGGKGEKR241KRETDDEGED
251-251251D
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
27 Leucine-rich repeat domain superfamily Acidic leucine-rich nuclear phosphoprotein 32 - -
GPS-Palm: 0.85
Deep-Palm: 0.97
114 - - -
GPS-Palm: 0.76
Deep-Palm: 0.98
123 SWISSPALM DBPTM CYSMODDB Leucine Rich repeats (2 copies)
SW480 cell line (26865113)
Unknown (32651440)
GPS-Palm: 0.76
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
HAP1 cell
Specificity: 0.500
1/1 (100.0%)
1
293T cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
144 Y → C 0.002288 SNP Missense Mutation STAD
237 G → C 0.001887 SNP Missense Mutation UCEC