Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q969X5-2 | ERGIC1 | Endoplasmic reticulum-Golgi intermediate compartment protein … | Homo sapiens (Human) | 198 aa |
Protein Details: Q969X5-2 (ERGIC1)
Protein Information
| Accession | Q969X5-2 |
|---|---|
| Protein Names | Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32) |
| Gene Symbol | ERGIC1 |
| Organism | Homo sapiens (Human) |
| Length | 198 aa |
| Isoforms | |
| Related PMIDs | 31251020 32651440 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGRHEVGHID11NSMKIPLNNG21AGCRFEGQFS31INKVPGNFHV41STHSATAQPQ
51-10051NPDMTHVIHK61LSFGDTLQVQ71NIHGAFNALG81GADRLTSNPL91ASHDYILKIV
101-150101PTVYEDKSGK111QRYSYQYTVA121NKEYVAYSHT131GRIIPAIWFR141YDLSPITVKY
151-198151TERRQPLYRF161ITTICAIIGG171TFTVAGILDS181CIFTASEAWK191KIQLGKMH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 23 | Endoplasmic reticulum vesicle transporter, C-terminal Endoplasmic reticulum vesicle transporter | - | - |
GPS-Palm: 0.87
|
|
| 31 | - | - | - |
Deep-Palm: 0.39
|
|
| 32 | - | - | - |
Deep-Palm: 0.42
|
|
| 33 | - | - | - |
Deep-Palm: 0.43
|
|
| 82 | - | - | - |
Deep-Palm: 0.87
|
|
| 115 | - | - | - |
Deep-Palm: 0.30
|
|
| 165 | - | - | - |
GPS-Palm: 0.76
|
|
| 181 | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.74
|
|
| 257 | - | - | - |
Deep-Palm: 0.66
|
|
| 273 | - | - | - |
Deep-Palm: 0.75
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
LNCaP
Specificity: 0.667
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.167
1/1 (100.0%)
1
heart
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 115 | C → S | 0.002294 | SNP | Missense Mutation | OV |
| 209 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 273 | C → Afs*64 | 0.002294 | DEL | Frame Shift Del | OV |