Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96DZ5 | CLIP3 | CAP-Gly domain-containing linker protein 3 … | Homo sapiens (Human) | 547 aa |
Protein Details: Q96DZ5 (CLIP3)
Protein Information
| Accession | Q96DZ5 |
|---|---|
| Protein Names | CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59) |
| Gene Symbol | CLIP3 |
| Organism | Homo sapiens (Human) |
| Length | 547 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTKTDPAPMA11PPPRGEEEEE21EEEDEPVPEA31PSPTQERRQK41PVVHPSAPAP
51-10051LPKDYAFTFF61DPNDPACQEI71LFDPQTTIPE81LFAIVRQWVP91QVQHKIDVIG
101-150101NEILRRGCHV111NDRDGLTDMT121LLHYACKAGA131HGVGDPAAAV141RLSQQLLALG
151-200151ADVTLRSRWT161NMNALHYAAY171FDVPDLVRVL181LKGARPRVVN191STCSDFNHGS
201-250201ALHIAASSLC211LGAAKCLLEH221GANPALRNRK231GQVPAEVVPD241PMDMSLDKAE
251-300251AALVAKELRT261LLEEAVPLSC271ALPKVTLPNY281DNVPGNLMLS291ALGLRLGDRV
301-350301LLDGQKTGTL311RFCGTTEFAS321GQWVGVELDE331PEGKNDGSVG341GVRYFICPPK
351-400351QGLFASVSKI361SKAVDAPPSS371VTSTPRTPRM381DFSRVTGKGR391REHKGKKKTP
401-450401SSPSLGSLQQ411RDGAKAEVGD421QVLVAGQKQG431IVRFYGKTDF441APGYWYGIEL
451-500451DQPTGKHDGS461VFGVRYFTCP471PRHGVFAPAS481RIQRIGGSTD491SPGDSVGAKK
501-547501VHQVTMTQPK511RTFTTVRTPK521DIASENSISR531LLFCCWFPWM541LRAEMQS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 67 | - | - | - |
Deep-Palm: 0.21
|
|
| 108 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.64
|
|
| 126 | - | - | - |
Deep-Palm: 0.88
|
|
| 193 | - | - | - |
Deep-Palm: 0.92
|
|
| 210 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.92
|
|
| 216 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.96
|
|
| 270 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.98
|
|
| 313 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.80
|
|
| 347 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.88
|
|
| 469 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.67
|
|
| 534 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.21
|
| 535 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.06
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Jurkat T cell
Specificity: 0.667
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Cerebral Cortex (Mass)
Specificity: 0.333
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 86 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 295 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 433 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 501 | V → Cfs*4 | 0.002288 | DEL | Frame Shift Del | STAD |