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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q96FZ2 HMCES; C3orf37; DC12; SRAPD1 Abasic site processing protein HMCES … Homo sapiens (Human) 354 aa

Protein Details: Q96FZ2 (HMCES)

Protein Information
Accession Q96FZ2
Protein Names Abasic site processing protein HMCES (EC 4.-.-.-) (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1)
Gene Symbol HMCES; C3orf37; DC12; SRAPD1
Organism Homo sapiens (Human)
Length 354 aa
Isoforms No isoforms
Related PMIDs 19801377 29733200 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.636
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
14
LNCaP cells
Specificity: 0.636
14/46 (30.4%)
4
HAP1 cells
Specificity: 0.182
4/10 (40.0%)
2
DU145 cells
Specificity: 0.091
2/2 (100.0%)
2
PC3 cells
Specificity: 0.091
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MCGRTSCHLP11RDVLTRACAY21QDRRGQQRLP31EWRDPDKYCP41SYNKSPQSNS
51-10051PVLLSRLHFE61KDADSSERII71APMRWGLVPS81WFKESDPSKL91QFNTTNCRSD
101-150101TVMEKRSFKV111PLGKGRRCVV121LADGFYEWQR131CQGTNQRQPY141FIYFPQIKTE
151-200151KSGSIGAADS161PENWEKVWDN171WRLLTMAGIF181DCWEPPEGGD191VLYSYTIITV
201-250201DSCKGLSDIH211HRMPAILDGE221EAVSKWLDFG231EVSTQEALKL241IHPTENITFH
251-300251AVSSVVNNSR261NNTPECLAPV271DLVVKKELRA281SGSSQRMLQW291LATKSPKKED
301-350301SKTPQKEESD311VPQWSSQFLQ321KSPLPTKRGT331AGLLEQWLKR341EKEEEPVAKR
351-354351PYSQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
2 Prediction (High) - -
7 Prediction (High) - -
18 Prediction (Medium) - -
97 Prediction (Medium) - -
118 Prediction (High) - -
182 Prediction (Medium) - -
266 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
68 R → C 0.001887 SNP Missense Mutation UCEC
98 R → C 0.008130 SNP Missense Mutation THYM
143 Y → C 0.001969 SNP Missense Mutation HNSC
253 S → C 0.001969 SNP Missense Mutation HNSC
290 W → C 0.001969 SNP Missense Mutation LGG
350 R → C 0.002506 SNP Missense Mutation COAD