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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q96G23 CERS2; LASS2; TMSG1 Ceramide synthase 2 (CerS2) (LAG1 … Homo sapiens (Human) 380 aa

Protein Details: Q96G23 (CERS2)

Protein Information
Accession Q96G23
Protein Names Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297)
Gene Symbol CERS2; LASS2; TMSG1
Organism Homo sapiens (Human)
Length 380 aa
Isoforms No isoforms
Related PMIDs 19137006 29733200 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.586
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
17
LNCaP cells
Specificity: 0.586
17/46 (37.0%)
6
293T cells
Specificity: 0.207
6/10 (60.0%)
3
Jurkat T cells
Specificity: 0.103
3/25 (12.0%)
3
PC3 cells
Specificity: 0.103
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLQTLYDYFW11WERLWLPVNL21TWADLEDRDG31RVYAKASDLY41ITLPLALLFL
51-10051IVRYFFELYV61ATPLAALLNI71KEKTRLRAPP81NATLEHFYLT91SGKQPKQVEV
101-150101ELLSRQSGLS111GRQVERWFRR121RRNQDRPSLL131KKFREASWRF141TFYLIAFIAG
151-200151MAVIVDKPWF161YDMKKVWEGY171PIQSTIPSQY181WYYMIELSFY191WSLLFSIASD
201-250201VKRKDFKEQI211IHHVATIILI221SFSWFANYIR231AGTLIMALHD241SSDYLLESAK
251-300251MFNYAGWKNT261CNNIFIVFAI271VFIITRLVIL281PFWILHCTLV291YPLELYPAFF
301-350301GYYFFNSMMG311VLQLLHIFWA321YLILRMAHKF331ITGKLVEDER341SDREETESSE
351-380351GEEAAAGGGA361KSRPLANGHP371ILNNNHRKND
Palmitoylation Sites Details

No known palmitoylation sites

Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
88 Y → C 0.002033 SNP Missense Mutation LUSC
180 Y → C 0.001969 SNP Missense Mutation HNSC
224 W → C 0.001887 SNP Missense Mutation UCEC
287 C → G 0.002545 SNP Missense Mutation GBM
302 Y → C 0.002294 SNP Missense Mutation OV
319 W → C 0.001969 SNP Missense Mutation HNSC