Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96HE7 | ERO1A; ERO1L; UNQ434/PRO865 | ERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) … | Homo sapiens (Human) | 468 aa |
Protein Details: Q96HE7 (ERO1A)
Protein Information
| Accession | Q96HE7 |
|---|---|
| Protein Names | ERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein) (Endoplasmic reticulum oxidoreductase alpha) (Oxidoreductin-1-L-alpha) |
| Gene Symbol | ERO1A; ERO1L; UNQ434/PRO865 |
| Organism | Homo sapiens (Human) |
| Length | 468 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.738
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
31
LNCaP cells
Specificity: 0.738
31/46 (67.4%)
4
293T cells
Specificity: 0.095
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.095
4/4 (100.0%)
2
PC3 cells
Specificity: 0.048
2/4 (50.0%)
1
Endothelial cells
Specificity: 0.024
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGRGWGFLFG11LLGAVWLLSS21GHGEEQPPET31AAQRCFCQVS41GYLDDCTCDV
51-10051ETIDRFNNYR61LFPRLQKLLE71SDYFRYYKVN81LKRPCPFWND91ISQCGRRDCA
101-150101VKPCQSDEVP111DGIKSASYKY121SEEANNLIEE131CEQAERLGAV141DESLSEETQK
151-200151AVLQWTKHDD161SSDNFCEADD171IQSPEAEYVD181LLLNPERYTG191YKGPDAWKIW
201-250201NVIYEENCFK211PQTIKRPLNP221LASGQGTSEE231NTFYSWLEGL241CVEKRAFYRL
251-300251ISGLHASINV261HLSARYLLQE271TWLEKKWGHN281ITEFQQRFDG291ILTEGEGPRR
301-350301LKNLYFLYLI311ELRALSKVLP321FFERPDFQLF331TGNKIQDEEN341KMLLLEILHE
351-400351IKSFPLHFDE361NSFFAGDKKE371AHKLKEDFRL381HFRNISRIMD391CVGCFKCRLW
401-450401GKLQTQGLGT411ALKILFSEKL421IANMPESGPS431YEFHLTRQEI441VSLFNAFGRI
451-468451STSVKELENF461RNLLQNIH
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 85 | Prediction (Low) | - | - |
| 241 | Prediction (Medium) | - | - |
| 391 | Prediction (High) | - | - |
| 394 | Prediction (High) | - | - |
| 397 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 76 | Y → C | 0.002033 | SNP | Missense Mutation | THCA |
| 85 | C → C | 0.001887 | SNP | Silent | UCEC |
| 155 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 208 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 365 | A → Cfs*4 | 0.001764 | INS | Frame Shift Ins | LUAD |
| 391 | C → C | 0.001969 | SNP | Silent | LGG |
| 397 | C → C | 0.001887 | SNP | Silent | UCEC |