Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q96HE7 ERO1A ERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) … Homo sapiens (Human) 468 aa

Protein Details: Q96HE7 (ERO1A)

Protein Information
AccessionQ96HE7
Protein NamesERO1-like protein alpha (ERO1-L) (ERO1-L-alpha) (EC 1.8.3.2) (Endoplasmic oxidoreductin-1-like protein) (Endoplasmic reticulum oxidoreductase alpha) (Oxidoreductin-1-L-alpha)
Gene SymbolERO1A
OrganismHomo sapiens (Human)
Length468 aa
IsoformsNo isoforms
Related PMIDs 24357059 29733200 31251020 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGRGWGFLFG11LLGAVWLLSS21GHGEEQPPET31AAQRCFCQVS41GYLDDCTCDV
51-10051ETIDRFNNYR61LFPRLQKLLE71SDYFRYYKVN81LKRPCPFWND91ISQCGRRDCA
101-150101VKPCQSDEVP111DGIKSASYKY121SEEANNLIEE131CEQAERLGAV141DESLSEETQK
151-200151AVLQWTKHDD161SSDNFCEADD171IQSPEAEYVD181LLLNPERYTG191YKGPDAWKIW
201-250201NVIYEENCFK211PQTIKRPLNP221LASGQGTSEE231NTFYSWLEGL241CVEKRAFYRL
251-300251ISGLHASINV261HLSARYLLQE271TWLEKKWGHN281ITEFQQRFDG291ILTEGEGPRR
301-350301LKNLYFLYLI311ELRALSKVLP321FFERPDFQLF331TGNKIQDEEN341KMLLLEILHE
351-400351IKSFPLHFDE361NSFFAGDKKE371AHKLKEDFRL381HFRNISRIMD391CVGCFKCRLW
401-450401GKLQTQGLGT411ALKILFSEKL421IANMPESGPS431YEFHLTRQEI441VSLFNAFGRI
451-468451STSVKELENF461RNLLQNIH
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
35 - - -
Deep-Palm: 0.12
37 - - -
Deep-Palm: 0.12
46 Endoplasmic reticulum oxidoreductin 1 - -
Deep-Palm: 0.07
48 Endoplasmic reticulum oxidoreductin 1 - -
Deep-Palm: 0.05
85 - - -
GPS-Palm: 0.73
Deep-Palm: 0.06
94 - - -
Deep-Palm: 0.10
99 - -
cerebral cortex (36430497)
Deep-Palm: 0.08
104 - -
cerebral cortex (36430497)
Deep-Palm: 0.40
131 - -
Unknown (32651440)
Deep-Palm: 0.92
166 - -
Unknown (32651440)
Deep-Palm: 0.09
208 - - -
Deep-Palm: 0.41
241 - - -
GPS-Palm: 0.81
Deep-Palm: 0.94
391 - - -
GPS-Palm: 0.93
Deep-Palm: 0.12
394 - - -
GPS-Palm: 0.92
Deep-Palm: 0.18
397 - - -
GPS-Palm: 0.86
Deep-Palm: 0.25
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
cerebral cortex
Specificity: 0.267
4/4 (100.0%)
3
LNCaP
Specificity: 0.200
3/3 (100.0%)
2
PC3
Specificity: 0.133
2/2 (100.0%)
1
293T cell
Specificity: 0.067
1/1 (100.0%)
1
HUVECs
Specificity: 0.067
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.267
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine