Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96HY7 | DHTKD1; KIAA1630 | 2-oxoadipate dehydrogenase complex component E1 … | Homo sapiens (Human) | 919 aa |
Protein Details: Q96HY7 (DHTKD1)
Protein Information
| Accession | Q96HY7 |
|---|---|
| Protein Names | 2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial) |
| Gene Symbol | DHTKD1; KIAA1630 |
| Organism | Homo sapiens (Human) |
| Length | 919 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
20
LNCaP cells
Specificity: 1.000
20/46 (43.5%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASATAAAAR11RGLGRALPLF21WRGYQTERGV31YGYRPRKPES41REPQGALERP
51-10051PVDHGLARLV61TVYCEHGHKA71AKINPLFTGQ81ALLENVPEIQ91ALVQTLQGPF
101-150101HTAGLLNMGK111EEASLEEVLV121YLNQIYCGQI131SIETSQLQSQ141DEKDWFAKRF
151-200151EELQKETFTT161EERKHLSKLM171LESQEFDHFL181ATKFSTVKRY191GGEGAESMMG
201-250201FFHELLKMSA211YSGITDVIIG221MPHRGRLNLL231TGLLQFPPEL241MFRKMRGLSE
251-300251FPENFSATGD261VLSHLTSSVD271LYFGAHHPLH281VTMLPNPSHL291EAVNPVAVGK
301-350301TRGRQQSRQD311GDYSPDNSAQ321PGDRVICLQV331HGDASFCGQG341IVPETFTLSN
351-400351LPHFRIGGSV361HLIVNNQLGY371TTPAERGRSS381LYCSDIGKLV391GCAIIHVNGD
401-450401SPEEVVRATR411LAFEYQRQFR421KDVIIDLLCY431RQWGHNELDE441PFYTNPIMYK
451-500451IIRARKSIPD461TYAEHLIAGG471LMTQEEVSEI481KSSYYAKLND491HLNNMAHYRP
501-550501PALNLQAHWQ511GLAQPEAQIT521TWSTGVPLDL531LRFVGMKSVE541VPRELQMHSH
551-600551LLKTHVQSRM561EKMMDGIKLD571WATAEALALG581SLLAQGFNVR591LSGQDVGRGT
601-650601FSQRHAIVVC611QETDDTYIPL621NHMDPNQKGF631LEVSNSPLSE641EAVLGFEYGM
651-700651SIESPKLLPL661WEAQFGDFFN671GAQIIFDTFI681SGGEAKWLLQ691SGIVILLPHG
701-750701YDGAGPDHSS711CRIERFLQMC721DSAEEGVDGD731TVNMFVVHPT741TPAQYFHLLR
751-800751RQMVRNFRKP761LIVASPKMLL771RLPAAVSTLQ781EMAPGTTFNP791VIGDSSVDPK
801-850801KVKTLVFCSG811KHFYSLVKQR821ESLGAKKHDF831AIIRVEELCP841FPLDSLQQEM
851-900851SKYKHVKDHI861WSQEEPQNMG871PWSFVSPRFE881KQLACKLRLV891GRPPLPVPAV
901-919901GIGTVHLHQH911EDILAKTFA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 64 | Prediction (Low) | - | - |
| 429 | Prediction (High) | - | - |
| 808 | Prediction (High) | - | - |
| 839 | Prediction (Medium) | - | - |
| 885 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 173 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 302 | R → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 391 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 417 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 417 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 448 | M → Cfs*25 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 485 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 558 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 679 | F → C | 0.002020 | SNP | Missense Mutation | PRAD |