Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96K21-4 | ZFYVE19 | Abscission/NoCut checkpoint regulator (ANCHR) (MLL … | Homo sapiens (Human) | 296 aa |
Protein Details: Q96K21-4 (ZFYVE19)
Protein Information
| Accession | Q96K21-4 |
|---|---|
| Protein Names | Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) |
| Gene Symbol | ZFYVE19 |
| Organism | Homo sapiens (Human) |
| Length | 296 aa |
| Isoforms | |
| Related PMIDs | 29575903 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MIAERLARLR11QENKPKLVPS21QAEIEARLAA31LKDERQGSIP41STQEMEARLA
51-10051ALQGRVLPSQ61TPQPAHHTPD71TRTQAQQTQD81LLTQLAAEVA91IDESWKGGGP
101-150101AASLQNDLNQ111GGPGSTNSKR121QANWSLEEEK131SRLLAEAALE141LREENTRQER
151-200151ILALAKRLAM161LRGQDPERVT171LQDYRLPDSD181DDEDEETAIQ191RVLQQLTEEA
201-250201SLDEASGFNI211PAEQASRPWT221QPRGAEPEAQ231DVDPRPEAEE241EELPWCCICN
251-296251EDATLRCAGC261DGDLFCARCF271REGHDAFELK281EHQTSAYSPP291RAGQEH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 18 | - | - | - |
Deep-Palm: 0.97
|
|
| 80 | - | - | - |
Deep-Palm: 0.90
|
|
| 83 | - | - | - |
Deep-Palm: 0.81
|
|
| 96 | - | - | - |
Deep-Palm: 0.09
|
|
| 99 | - | - | - |
Deep-Palm: 0.17
|
|
| 104 | - | - | - |
Deep-Palm: 0.23
|
|
| 107 | - | - | - |
Deep-Palm: 0.20
|
|
| 125 | - | - | - |
Deep-Palm: 0.45
|
|
| 128 | - | - | - |
Deep-Palm: 0.40
|
|
| 421 | - | - | - |
Deep-Palm: 0.14
|
|
| 422 | - | - | - |
Deep-Palm: 0.17
|
|
| 424 | - | - | - |
Deep-Palm: 0.20
|
|
| 432 | - | - | - |
Deep-Palm: 0.06
|
|
| 435 | - | - | - |
Deep-Palm: 0.03
|
|
| 441 | - | - | - |
Deep-Palm: 0.37
|
|
| 444 | - | - | - |
Deep-Palm: 0.20
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
2
HeLa cell
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 125 | C → Sfs*8 | 0.002294 | DEL | Frame Shift Del | OV |
| 136 | S → C | 0.002294 | SNP | Missense Mutation | OV |
| 143 | W → C | 0.002545 | SNP | Missense Mutation | GBM |
| 435 | C → C | 0.003774 | SNP | Silent | UCEC |
| 460 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 466 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |