Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96LJ7 | DHRS1; SDR19C1 | Dehydrogenase/reductase SDR family member 1 … | Homo sapiens (Human) | 313 aa |
Protein Details: Q96LJ7 (DHRS1)
Protein Information
| Accession | Q96LJ7 |
|---|---|
| Protein Names | Dehydrogenase/reductase SDR family member 1 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 19C member 1) (Protein SDR19C1) |
| Gene Symbol | DHRS1; SDR19C1 |
| Organism | Homo sapiens (Human) |
| Length | 313 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 37611173 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
4
HAP1 cells
Specificity: 0.143
4/10 (40.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAPMNGQVC11VVTGASRGIG21RGIALQLCKA31GATVYITGRH41LDTLRVVAQE
51-10051AQSLGGQCVP61VVCDSSQESE71VRSLFEQVDR81EQQGRLDVLV91NNAYAGVQTI
101-150101LNTRNKAFWE111TPASMWDDIN121NVGLRGHYFC131SVYGARLMVP141AGQGLIVVIS
151-200151SPGSLQYMFN161VPYGVGKAAC171DKLAADCAHE181LRRHGVSCVS191LWPGIVQTEL
201-250201LKEHMAKEEV211LQDPVLKQFK221SAFSSAETTE231LSGKCVVALA241TDPNILSLSG
251-300251KVLPSCDLAR261RYGLRDVDGR271PVQDYLSLSS281VLSHVSGLGW291LASYLPSFLR
301-313301VPKWIIALYT311SKF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 10 | Prediction (Medium) | - | - |
| 28 | Prediction (High) | - | - |
| 130 | Prediction (Medium) | - | - |
| 177 | Prediction (High) | - | - |
| 188 | Prediction (Low) | - | - |
| 235 | Experimental | - | 37611173 |
| 256 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 18 | G → C | 0.002294 | SNP | Missense Mutation | OV |
| 261 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 275 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 300 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |