Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96NW4 | ANKRD27; PP12899 | Ankyrin repeat domain-containing protein 27 … | Homo sapiens (Human) | 1050 aa |
Protein Details: Q96NW4 (ANKRD27)
Protein Information
| Accession | Q96NW4 |
|---|---|
| Protein Names | Ankyrin repeat domain-containing protein 27 (VPS9 domain-containing protein) |
| Gene Symbol | ANKRD27; PP12899 |
| Organism | Homo sapiens (Human) |
| Length | 1050 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.909
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
10
LNCaP cells
Specificity: 0.909
10/46 (21.7%)
1
U937 cells
Specificity: 0.091
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MALYDEDLLK11NPFYLALQKC21RPDLCSKVAQ31IHGIVLVPCK41GSLSSSIQST
51-10051CQFESYILIP61VEEHFQTLNG71KDVFIQGNRI81KLGAGFACLL91SVPILFEETF
101-150101YNEKEESFSI111LCIAHPLEKR121ESSEEPLAPS131DPFSLKTIED141VREFLGRHSE
151-200151RFDRNIASFH161RTFRECERKS171LRHHIDSANA181LYTKCLQQLL191RDSHLKMLAK
201-250201QEAQMNLMKQ211AVEIYVHHEI221YNLIFKYVGT231MEASEDAAFN241KITRSLQDLQ
251-300251QKDIGVKPEF261SFNIPRAKRE271LAQLNKCTSP281QQKLVCLRKV291VQLITQSPSQ
301-350301RVNLETMCAD311DLLSVLLYLL321VKTEIPNWMA331NLSYIKNFRF341SSLAKDELGY
351-400351CLTSFEAAIE361YIRQGSLSAK371PPESEGFGDR381LFLKQRMSLL391SQMTSSPTDC
401-450401LFKHIASGNQ411KEVERLLSQE421DHDKDTVQKM431CHPLCFCDDC441EKLVSGRLND
451-500451PSVVTPFSRD461DRGHTPLHVA471AVCGQASLID481LLVSKGAMVN491ATDYHGATPL
501-550501HLACQKGYQS511VTLLLLHYKA521SAEVQDNNGN531TPLHLACTYG541HEDCVKALVY
551-600551YDVESCRLDI561GNEKGDTPLH571IAARWGYQGV581IETLLQNGAS591TEIQNRLKET
601-650601PLKCALNSKI611LSVMEAYHLS621FERRQKSSEA631PVQSPQRSVD641SISQESSTSS
651-700651FSSMSASSRQ661EETKKDYREV671EKLLRAVADG681DLEMVRYLLE691WTEEDLEDAE
701-750701DTVSAADPEF711CHPLCQCPKC721APAQKRLAKV731PASGLGVNVT741SQDGSSPLHV
751-800751AALHGRADLI761PLLLKHGANA771GARNADQAVP781LHLACQQGHF791QVVKCLLDSN
801-850801AKPNKKDLSG811NTPLIYACSG821GHHELVALLL831QHGASINASN841NKGNTALHEA
851-900851VIEKHVFVVE861LLLLHGASVQ871VLNKRQRTAV881DCAEQNSKIM891ELLQVVPSCV
901-950901ASLDDVAETD911RKEYVTVKIR921KKWNSKLYDL931PDEPFTRQFY941FVHSAGQFKG
951-1000951KTSREIMARD961RSVPNLTEGS971LHEPGRQSVT981LRQNNLPAQS991GSHAAEKGNS
1001-10501001DWPERPGLTQ1011TGPGHRRMLR1021RHTVEDAVVS1031QGPEAAGPLS1041TPQEVSASRS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 20 | Prediction (Medium) | - | - |
| 25 | Prediction (Low) | - | - |
| 39 | Prediction (Low) | - | - |
| 88 | Prediction (Medium) | - | - |
| 112 | Prediction (Low) | - | - |
| 166 | Prediction (Low) | - | - |
| 277 | Prediction (Medium) | - | - |
| 286 | Prediction (Medium) | - | - |
| 351 | Prediction (Low) | - | - |
| 504 | Prediction (Low) | - | - |
| 604 | Prediction (Medium) | - | - |
| 720 | Prediction (Low) | - | - |
| 882 | Prediction (Medium) | - | - |
| 899 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 39 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 266 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 431 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 431 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 504 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 574 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 612 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 715 | C → C | 0.002141 | SNP | Silent | SKCM |