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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q96P11-3 NSUN5 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) … Homo sapiens (Human) 324 aa

Protein Details: Q96P11-3 (NSUN5)

Protein Information
AccessionQ96P11-3
Protein Names28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein)
Gene SymbolNSUN5
OrganismHomo sapiens (Human)
Length324 aa
Isoforms
Related PMIDs 31251020
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLRAFLFLSL11FPHSQVLVYE21LLLGKGFRGG31GGRWKALLGR41HQARLKAELA
51-10051RLKVHRGVSR61NEDLLEVGSR71PGPASQLPRF81VRVNTLKTCS91DDVVDYFKRQ
101-150101GFSYQGRASS111LDDLRALKGK121HFLLDPLMPE131LLVFPAQTDL141HEHPLYRAGH
151-200151LILQDRASCL161PAMLLDPPPG171SHVIDACAAP181GNKTSHLAAL191LKNQGSLPLT
201-250201WMPSGWHPWP211RCWPGLASLA221VNWLRRTSWR231SPPRIHATMR241STTSCWILPA
251-300251VARVCRADSW261RSPGQAHLAR271CVCMPWQGSS281SEPCATRSLS291LPCSGSSTPR
301-324301APSARRRMKT311WCEMRCSRTR321APSG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 - - -
Deep-Palm: 0.82
146 - - -
Deep-Palm: 0.91
216 - - -
Deep-Palm: 0.96
234 - - -
Deep-Palm: 0.96
278 - - -
Deep-Palm: 0.98
279 - - -
Deep-Palm: 0.98
308 - - -
Deep-Palm: 0.77
343 - - -
Deep-Palm: 0.98
359 - - -
Deep-Palm: 0.95
362 - - -
Deep-Palm: 0.92
404 - - -
Deep-Palm: 0.90
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
158 G → C 0.001887 SNP Missense Mutation UCEC
216 C → Y 0.001887 SNP Missense Mutation UCEC
330 R → C 0.002506 SNP Missense Mutation COAD