Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96P11-4 | NSUN5 | 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) … | Homo sapiens (Human) | 470 aa |
Protein Details: Q96P11-4 (NSUN5)
Protein Information
| Accession | Q96P11-4 |
|---|---|
| Protein Names | 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein) |
| Gene Symbol | NSUN5 |
| Organism | Homo sapiens (Human) |
| Length | 470 aa |
| Isoforms | |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLYAAAAGV11LAGVESRQGS21IKGLVYSSNF31QNVKQLYALV41CETQRYSAVL
51-10051DAVIASAGLL61RAEKKLRPHL71AKVLVYELLL81GKGFRGGGGR91WKALLGRHQA
101-150101RLKAELARLK111VHRGVSRNED121LLEVGSRPGP131ASQLPRFVRV141NTLKTCSDDV
151-200151VDYFKRQGFS161YQGRASSLDD171LRALKGKHFL181LDPLMPELLV191FPAQTDLHEH
201-250201PLYRAGHLIL211QDRASCLPAM221LLDPPPGSHV231IDACAAPGNK241TSHLAALLKN
251-300251QGKIFAFDLD261AKRLASMATL271LARAGVSCCE281LAEEDFLAVS291PSDPRYHEVH
301-350301YILLDPSCSG311SGMPSRQLEE321PGAGTPSPVR331LHALAGFQQR341ALCHALTFPS
351-400351LQRLVYSTCS361LCQEENEDVV371RDALQQNPGA381FRLAPALPAW391PHRGLSTFPG
401-450401AEHCLRASPE411TTLSSGFFVA421VIERVEVPSL431TGQSISTRTH441TQPSPKEKEE
451-470451TAKSRSRCLH461TALHIAEAPG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 41 | NSUN5/RCM1, N-terminal domain | - | - |
Deep-Palm: 0.82
|
|
| 146 | - | - | - |
Deep-Palm: 0.91
|
|
| 216 | - | - | - |
Deep-Palm: 0.96
|
|
| 234 | - | - | - |
Deep-Palm: 0.96
|
|
| 278 | - | - | - |
Deep-Palm: 0.98
|
|
| 279 | - | - | - |
Deep-Palm: 0.98
|
|
| 308 | - | - | - |
Deep-Palm: 0.77
|
|
| 343 | - | - | - |
Deep-Palm: 0.98
|
|
| 359 | - | - | - |
Deep-Palm: 0.95
|
|
| 362 | - | - | - |
Deep-Palm: 0.92
|
|
| 404 | - | - | - |
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 158 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 216 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 330 | R → C | 0.002506 | SNP | Missense Mutation | COAD |