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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q96QE2 SLC2A13 Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) … Homo sapiens (Human) 648 aa

Protein Details: Q96QE2 (SLC2A13)

Protein Information
Accession Q96QE2
Protein Names Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)
Gene Symbol SLC2A13
Organism Homo sapiens (Human)
Length 648 aa
Isoforms No isoforms
Related PMIDs 29575903 33636221 36430497 37611173
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
Liver membrane
Specificity: 0.200
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSRKASENVE11YTLRSLSSLM21GERRRKQPEP31DAASAAGECS41LLAAAESSTS
51-10051LQSAGAGGGG61VGDLERAARR71QFQQDETPAF81VYVVAVFSAL91GGFLFGYDTG
101-150101VVSGAMLLLK111RQLSLDALWQ121ELLVSSTVGA131AAVSALAGGA141LNGVFGRRAA
151-200151ILLASALFTA161GSAVLAAANN171KETLLAGRLV181VGLGIGIASM191TVPVYIAEVS
201-250201PPNLRGRLVT211INTLFITGGQ221FFASVVDGAF231SYLQKDGWRY241MLGLAAVPAV
251-300251IQFFGFLFLP261ESPRWLIQKG271QTQKARRILS281QMRGNQTIDE291EYDSIKNNIE
301-350301EEEKEVGSAG311PVICRMLSYP321PTRRALIVGC331GLQMFQQLSG341INTIMYYSAT
351-400351ILQMSGVEDD361RLAIWLASVT371AFTNFIFTLV381GVWLVEKVGR391RKLTFGSLAG
401-450401TTVALIILAL411GFVLSAQVSP421RITFKPIAPS431GQNATCTRYS441YCNECMLDPD
451-500451CGFCYKMNKS461TVIDSSCVPV471NKASTNEAAW481GRCENETKFK491TEDIFWAYNF
501-550501CPTPYSWTAL511LGLILYLVFF521APGMGPMPWT531VNSEIYPLWA541RSTGNACSSG
551-600551INWIFNVLVS561LTFLHTAEYL571TYYGAFFLYA581GFAAVGLLFI591YGCLPETKGK
601-648601KLEEIESLFD611NRLCTCGTSD621SDEGRYIEYI631RVKGSNYHLS641DNDASDVE
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
314 Experimental Prediction (High) - 37611173
330 Prediction (High) - -
467 Prediction (Medium) - -
547 Prediction (Medium) - -
593 Prediction (High) - -
614 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) - 29575903
616 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) - 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
283 R → C 0.002506 SNP Missense Mutation COAD
323 R → C 0.001887 SNP Missense Mutation UCEC
330 C → Y 0.002288 SNP Missense Mutation STAD
390 R → C 0.002141 SNP Missense Mutation SKCM
440 S → C 0.002033 SNP Missense Mutation LUSC
451 C → C 0.002288 SNP Silent STAD
451 C → C 0.001887 SNP Silent UCEC
453 F → C 0.001887 SNP Missense Mutation UCEC
467 C → C 0.002288 SNP Silent STAD
480 W → C 0.002506 SNP Missense Mutation COAD
516 Y → C 0.002020 SNP Missense Mutation PRAD
593 C → C 0.002033 SNP Silent LUSC