Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q96QE2 | SLC2A13 | Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) … | Homo sapiens (Human) | 648 aa |
Protein Details: Q96QE2 (SLC2A13)
Protein Information
| Accession | Q96QE2 |
|---|---|
| Protein Names | Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) |
| Gene Symbol | SLC2A13 |
| Organism | Homo sapiens (Human) |
| Length | 648 aa |
| Isoforms | No isoforms |
| Related PMIDs | 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRKASENVE11YTLRSLSSLM21GERRRKQPEP31DAASAAGECS41LLAAAESSTS
51-10051LQSAGAGGGG61VGDLERAARR71QFQQDETPAF81VYVVAVFSAL91GGFLFGYDTG
101-150101VVSGAMLLLK111RQLSLDALWQ121ELLVSSTVGA131AAVSALAGGA141LNGVFGRRAA
151-200151ILLASALFTA161GSAVLAAANN171KETLLAGRLV181VGLGIGIASM191TVPVYIAEVS
201-250201PPNLRGRLVT211INTLFITGGQ221FFASVVDGAF231SYLQKDGWRY241MLGLAAVPAV
251-300251IQFFGFLFLP261ESPRWLIQKG271QTQKARRILS281QMRGNQTIDE291EYDSIKNNIE
301-350301EEEKEVGSAG311PVICRMLSYP321PTRRALIVGC331GLQMFQQLSG341INTIMYYSAT
351-400351ILQMSGVEDD361RLAIWLASVT371AFTNFIFTLV381GVWLVEKVGR391RKLTFGSLAG
401-450401TTVALIILAL411GFVLSAQVSP421RITFKPIAPS431GQNATCTRYS441YCNECMLDPD
451-500451CGFCYKMNKS461TVIDSSCVPV471NKASTNEAAW481GRCENETKFK491TEDIFWAYNF
501-550501CPTPYSWTAL511LGLILYLVFF521APGMGPMPWT531VNSEIYPLWA541RSTGNACSSG
551-600551INWIFNVLVS561LTFLHTAEYL571TYYGAFFLYA581GFAAVGLLFI591YGCLPETKGK
601-648601KLEEIESLFD611NRLCTCGTSD621SDEGRYIEYI631RVKGSNYHLS641DNDASDVE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | - | - | - |
Deep-Palm: 0.96
|
|
| 314 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.91
Deep-Palm: 0.96
|
|
| 330 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.71
|
|
| 436 | - | - | - |
Deep-Palm: 0.02
|
|
| 442 | - | - | - |
Deep-Palm: 0.01
|
|
| 445 | - | - | - |
Deep-Palm: 0.01
|
|
| 451 | - | - | - |
Deep-Palm: 0.02
|
|
| 454 | - | - | - |
Deep-Palm: 0.02
|
|
| 467 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.81
Deep-Palm: 0.35
|
|
| 483 | - | - | - |
Deep-Palm: 0.41
|
|
| 501 | - | - | - |
Deep-Palm: 0.63
|
|
| 547 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.26
|
|
| 593 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
|
| 614 | SWISSPALM DBPTM CYSMODDB | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.84
Deep-Palm: 0.89
|
| 616 | SWISSPALM DBPTM CYSMODDB | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.77
Deep-Palm: 0.84
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
heart
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.444
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 283 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 323 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 330 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 390 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 440 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 451 | C → C | 0.002288 | SNP | Silent | STAD |
| 451 | C → C | 0.001887 | SNP | Silent | UCEC |
| 453 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 467 | C → C | 0.002288 | SNP | Silent | STAD |
| 480 | W → C | 0.002506 | SNP | Missense Mutation | COAD |
| 516 | Y → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 593 | C → C | 0.002033 | SNP | Silent | LUSC |