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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q96RQ1 ERGIC2; ERV41; PTX1; CDA14 Endoplasmic reticulum-Golgi intermediate compartment protein … Homo sapiens (Human) 377 aa

Protein Details: Q96RQ1 (ERGIC2)

Protein Information
Accession Q96RQ1
Protein Names Endoplasmic reticulum-Golgi intermediate compartment protein 2
Gene Symbol ERGIC2; ERV41; PTX1; CDA14
Organism Homo sapiens (Human)
Length 377 aa
Isoforms No isoforms
Related PMIDs 19137006 26111759 29575903 29733200 31251020 32944167 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.630
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
29
LNCaP cells
Specificity: 0.630
29/46 (63.0%)
6
Jurkat T cells
Specificity: 0.130
6/25 (24.0%)
4
HAP1 cells
Specificity: 0.087
4/10 (40.0%)
3
PC3 cells
Specificity: 0.065
3/4 (75.0%)
2
T cells
Specificity: 0.043
2/4 (50.0%)
1
HeLa cells
Specificity: 0.022
1/1 (100.0%)
1
Liver membrane
Specificity: 0.022
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRRLNRKKTL11SLVKELDAFP21KVPESYVETS31ASGGTVSLIA41FTTMALLTIM
51-10051EFSVYQDTWM61KYEYEVDKDF71SSKLRINIDI81TVAMKCQYVG91ADVLDLAETM
101-150101VASADGLVYE111PTVFDLSPQQ121KEWQRMLQLI131QSRLQEEHSL141QDVIFKSAFK
151-200151STSTALPPRE161DDSSQSPNAC171RIHGHLYVNK181VAGNFHITVG191KAIPHPRGHA
201-250201HLAALVNHES211YNFSHRIDHL221SFGELVPAII231NPLDGTEKIA241IDHNQMFQYF
251-300251ITVVPTKLHT261YKISADTHQF271SVTERERIIN281HAAGSHGVSG291IFMKYDLSSL
301-350301MVTVTEEHMP311FWQFFVRLCG321IVGGIFSTTG331MLHGIGKFIV341EIICCRFRLG
351-377351SYKPVNSVPF361EDGHTDNHLP371LLENNTH
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
319 Prediction (Medium) - -
344 Prediction (High) - -
345 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
34 G → C 0.001887 SNP Missense Mutation UCEC
249 Y → C 0.002033 SNP Missense Mutation LUSC
277 R → C 0.001969 SNP Missense Mutation LGG