Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99460-2 | PSMD1 | 26S proteasome non-ATPase regulatory subunit … | Homo sapiens (Human) | 922 aa |
Protein Details: Q99460-2 (PSMD1)
Protein Information
| Accession | Q99460-2 |
|---|---|
| Protein Names | 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) |
| Gene Symbol | PSMD1 |
| Organism | Homo sapiens (Human) |
| Length | 922 aa |
| Isoforms | |
| Related PMIDs | 31251020 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MITSAAGIIS11LLDEDEPQLK21EFALHKLNAV31VNDFWAEISE41SVDKIEVLYE
51-10051DEGFRSRQFA61ALVASKVFYH71LGAFEESLNY81ALGAGDLFNV91NDNSEYVETI
101-150101IAKCIDHYTK111QCVENADLPE121GEKKPIDQRL131EGIVNKMFQR141CLDDHKYKQA
151-200151IGIALETRRL161DVFEKTILES171NDVPGMLAYS181LKLCMSLMQN191KQFRNKVLRV
201-250201LVKIYMNLEK211PDFINVCQCL221IFLDDPQAVS231DILEKLVKED241NLLMAYQICF
251-300251DLYESASQQF261LSSVIQNLRT271VGTPIASVPG281STNTGTVPGS291EKDSDSMETE
301-350301EKTSSAFVGK311TPEASPEPKD321QTLKMIKILS331GEMAIELHLQ341FLIRNNNTDL
351-400351MILKNTKDAV361RNSVCHTATV371IANSFMHCGT381TSDQFLRDNL391EWLARATNWA
401-450401KFTATASLGV411IHKGHEKEAL421QLMATYLPKD431TSPGSAYQEG441GGLYALGLIH
451-500451ANHGGDIIDY461LLNQLKNASN471DIVRHGGSLG481LGLAAMGTAR491QDVYDLLKTN
501-550501LYQDDAVTGE511AAGLALGLVM521LGSKNAQAIE531DMVGYAQETQ541HEKILRGLAV
551-600551GIALVMYGRM561EEADALIESL571CRDKDPILRR581SGMYTVAMAY591CGSGNNKAIR
601-650601RLLHVAVSDV611NDDVRRAAVE621SLGFILFRTP631EQCPSVVSLL641SESYNPHVRY
651-700651GAAMALGICC661AGTGNKEAIN671LLEPMTNDPV681NYVRQGALIA691SALIMIQQTE
701-750701ITCPKVNQFR711QLYSKVINDK721HDDVMAKFGA731ILAQGILDAG741GHNVTISLQS
751-800751RTGHTHMPSV761VGVLVFTQFW771FWFPLSHFLS781LAYTPTCVIG791LNKDLKVSTA
801-850801VLSITAKAKK811KEKEKEKKEE821EKMEVDEAEK831KEEKEKKKEP841EPNFQLLDNP
851-900851ARVMPAQLKV861LTMPETCRYQ871PFKPLSIGGI881IILKDTSEDI891EELVEPVAAH
901-922901GPKIEEEEQE911PEPPEPFEYI921DD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 104 | - | - | - |
Deep-Palm: 0.04
|
|
| 112 | - | - | - |
Deep-Palm: 0.62
|
|
| 141 | - | - | - |
Deep-Palm: 0.80
|
|
| 184 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.87
|
|
| 217 | - | - | - |
Deep-Palm: 0.46
|
|
| 219 | - | - | - |
Deep-Palm: 0.67
|
|
| 249 | - | - | - |
Deep-Palm: 0.79
|
|
| 365 | - | - | - |
Deep-Palm: 0.56
|
|
| 378 | - | - | - |
Deep-Palm: 0.47
|
|
| 571 | - | - | - |
Deep-Palm: 0.95
|
|
| 591 | - | - | - |
Deep-Palm: 0.96
|
|
| 633 | - |
HeLa
(29575903)
| - |
Deep-Palm: 0.96
|
|
| 659 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.96
|
|
| 660 | - | - | - |
Deep-Palm: 0.97
|
|
| 703 | - | - | - |
Deep-Palm: 0.61
|
|
| 787 | - | - | - |
Deep-Palm: 0.86
|
|
| 806 | - | - | - |
Deep-Palm: 0.73
|
|
| 898 | - | - | - |
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 480 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 546 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 572 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 802 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 910 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |