Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99497 | PARK7 | Parkinson disease protein 7 (Maillard … | Homo sapiens (Human) | 189 aa |
Protein Details: Q99497 (PARK7)
Protein Information
| Accession | Q99497 |
|---|---|
| Protein Names | Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124) |
| Gene Symbol | PARK7 |
| Organism | Homo sapiens (Human) |
| Length | 189 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 29733200 31251020 31382980 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.464
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.464
13/46 (28.3%)
6
HAP1 cells
Specificity: 0.214
6/10 (60.0%)
4
293T cells
Specificity: 0.143
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.143
4/4 (100.0%)
1
U937 cells
Specificity: 0.036
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASKRALVIL11AKGAEEMETV21IPVDVMRRAG31IKVTVAGLAG41KDPVQCSRDV
51-10051VICPDASLED61AKKEGPYDVV71VLPGGNLGAQ81NLSESAAVKE91ILKEQENRKG
101-150101LIAAICAGPT111ALLAHEIGFG121SKVTTHPLAK131DKMMNGGHYT141YSENRVEKDG
151-189151LILTSRGPGT161SFEFALAIVE171ALNGKEVAAQ181VKAPLVLKD
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 46 | DBPTM SWISSPALM Prediction (Low) | DJ-1/PfpI family | - |
| 53 | CYSMODDB SWISSPALM DBPTM | DJ-1/PfpI family | - |
| 106 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | DJ-1/PfpI family | 29575903 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 145 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |