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UniProt ID Gene Symbol Protein Name Organism Length Action
Q99714-2 HSD17B10 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) … Homo sapiens (Human) 252 aa

Protein Details: Q99714-2 (HSD17B10)

Protein Information
AccessionQ99714-2
Protein Names3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH)
Gene SymbolHSD17B10
OrganismHomo sapiens (Human)
Length252 aa
Isoforms
Related PMIDs 31251020 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAACRSVKG11LVAVITGGAS21GLGLATAERL31VGQGASAVLL41DLPNSGGEAQ
51-10051AKKLGNNCVF61APADVTSEKD71VQTALALAKG81KFGRVDVAVN91CAGIAVASKT
101-150101YNLKKGQTHT111LEDFQRVLDV121NLMGTFNVIR131LVAGEMGQNE141PDQGGQRGVI
151-200151INTASVAAFE161GQVGQAAYSA171SKGGIVGMTL181PIARDLAPIG191LFGTPLLTSL
201-250201PEKVCNFLAS211QVPFPSRLGD221PAEYAHLVQA231IIENPFLNGE241VIRLDGAIRM
251-252251QP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
5 - - -
GPS-Palm: 0.93
Deep-Palm: 0.24
58 - - -
Deep-Palm: 0.97
91 - - -
Deep-Palm: 0.96
214 - - -
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
LNCaP
Specificity: 0.500
2/2 (100.0%)
2
PC3
Specificity: 0.500
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine