Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99732 | LITAF | Lipopolysaccharide-induced tumor necrosis factor-alpha factor … | Homo sapiens (Human) | 161 aa |
Protein Details: Q99732 (LITAF)
Protein Information
| Accession | Q99732 |
|---|---|
| Protein Names | Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein) |
| Gene Symbol | LITAF |
| Organism | Homo sapiens (Human) |
| Length | 161 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSVPGPYQAA11TGPSSAPSAP21PSYEETVAVN31SYYPTPPAPM41PGPTTGLVTG
51-10051PDGKGMNPPS61YYTQPAPIPN71NNPITVQTVY81VQHPITFLDR91PIQMCCPSCN
101-150101KMIVSQLSYN111AGALTWLSCG121SLCLLGCIAG131CCFIPFCVDA141LQDVDHYCPN
151-161151CRALLGTYKR161L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 95 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.04
|
|
| 96 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.04
|
|
| 99 | - | - | - |
Deep-Palm: 0.25
|
|
| 119 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.70
|
|
| 123 | - | - | - |
Deep-Palm: 0.64
|
|
| 127 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.53
|
|
| 131 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.13
|
|
| 132 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.20
|
|
| 137 | SWISSPALM DBPTM CYSMODDB | LITAF-like zinc ribbon domain |
HeLa
(29575903)
| - |
Deep-Palm: 0.33
|
| 148 | - | - | - |
Deep-Palm: 0.57
|
|
| 151 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.09
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 116 | W → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 137 | C → C | 0.001887 | SNP | Silent | UCEC |
| 160 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |