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UniProt ID Gene Symbol Protein Name Organism Length Action
Q99795 GPA33 Cell surface A33 antigen (Glycoprotein … Homo sapiens (Human) 319 aa

Protein Details: Q99795 (GPA33)

Protein Information
AccessionQ99795
Protein NamesCell surface A33 antigen (Glycoprotein A33)
Gene SymbolGPA33
OrganismHomo sapiens (Human)
Length319 aa
IsoformsNo isoforms
Related PMIDs 26111759
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVGKMWPVLW11TLCAVRVTVD21AISVETPQDV31LRASQGKSVT41LPCTYHTSTS
51-10051SREGLIQWDK61LLLTHTERVV71IWPFSNKNYI81HGELYKNRVS91ISNNAEQSDA
101-150101SITIDQLTMA111DNGTYECSVS121LMSDLEGNTK131SRVRLLVLVP141PSKPECGIEG
151-200151ETIIGNNIQL161TCQSKEGSPT171PQYSWKRYNI181LNQEQPLAQP191ASGQPVSLKN
201-250201ISTDTSGYYI211CTSSNEEGTQ221FCNITVAVRS231PSMNVALYVG241IAVGVVAALI
251-300251IIGIIIYCCC261CRGKDDNTED271KEDARPNREA281YEEPPEQLRE291LSREREEEDD
301-319301YRQEEQRSTG311RESPDHLDQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
13 - - -
GPS-Palm: 0.85
Deep-Palm: 0.10
43 Immunoglobulin-like fold Immunoglobulin V-set domain Cell surface A33 antigen - -
Deep-Palm: 0.79
117 - - -
Deep-Palm: 0.16
146 - - -
Deep-Palm: 0.98
162 - - -
GPS-Palm: 0.65
Deep-Palm: 0.37
211 - - -
Deep-Palm: 0.09
222 - - -
Deep-Palm: 0.10
258 - - -
GPS-Palm: 0.95
Deep-Palm: 0.91
259 - - -
GPS-Palm: 0.95
Deep-Palm: 0.91
260 - - -
GPS-Palm: 0.96
Deep-Palm: 0.91
261 - - -
GPS-Palm: 0.95
Deep-Palm: 0.86
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Primary T cell
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
98 S → C 0.002427 SNP Missense Mutation BLCA
207 G → C 0.001764 SNP Missense Mutation LUAD
260 C → C 0.001887 SNP Silent UCEC
261 C → R 0.002288 SNP Missense Mutation STAD
261 C → R 0.002506 SNP Missense Mutation COAD