Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99805 | TM9SF2 | Transmembrane 9 superfamily member 2 … | Homo sapiens (Human) | 663 aa |
Protein Details: Q99805 (TM9SF2)
Protein Information
| Accession | Q99805 |
|---|---|
| Protein Names | Transmembrane 9 superfamily member 2 (p76) |
| Gene Symbol | TM9SF2 |
| Organism | Homo sapiens (Human) |
| Length | 663 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 29575903 29733200 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.750
24/46 (52.2%)
4
HAP1 cells
Specificity: 0.125
4/10 (40.0%)
3
T cells
Specificity: 0.094
3/4 (75.0%)
1
PC3 cells
Specificity: 0.031
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSARLPVLSP11PRWPRLLLLS21LLLLGAVPGP31RRSGAFYLPG41LAPVNFCDEE
51-10051KKSDECKAEI61ELFVNRLDSV71ESVLPYEYTA81FDFCQASEGK91RPSENLGQVL
101-150101FGERIEPSPY111KFTFNKKETC121KLVCTKTYHT131EKAEDKQKLE141FLKKSMLLNY
151-200151QHHWIVDNMP161VTWCYDVEDG171QRFCNPGFPI181GCYITDKGHA191KDACVISSDF
201-250201HERDTFYIFN211HVDIKIYYHV221VETGSMGARL231VAAKLEPKSF241KHTHIDKPDC
251-300251SGPPMDISNK261ASGEIKIAYT271YSVSFEEDDK281IRWASRWDYI291LESMPHTHIQ
301-350301WFSIMNSLVI311VLFLSGMVAM321IMLRTLHKDI331ARYNQMDSTE341DAQEEFGWKL
351-400351VHGDIFRPPR361KGMLLSVFLG371SGTQILIMTF381VTLFFACLGF391LSPANRGALM
401-450401TCAVVLWVLL411GTPAGYVAAR421FYKSFGGEKW431KTNVLLTSFL441CPGIVFADFF
451-500451IMNLILWGEG461SSAAIPFGTL471VAILALWFCI481SVPLTFIGAY491FGFKKNAIEH
501-550501PVRTNQIPRQ511IPEQSFYTKP521LPGIIMGGIL531PFGCIFIQLF541FILNSIWSHQ
551-600551MYYMFGFLFL561VFIILVITCS571EATILLCYFH581LCAEDYHWQW591RSFLTSGFTA
601-650601VYFLIYAVHY611FFSKLQITGT621ASTILYFGYT631MIMVLIFFLF641TGTIGFFACF
651-663651WFVTKIYSVV661KVD
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 120 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Endomembrane protein 70 | - |
| 124 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Endomembrane protein 70 | - |
| 174 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | 29575903 |
| 182 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | 29575903 |
| 387 | Prediction (Medium) | - | - |
| 402 | Prediction (Low) | - | - |
| 479 | Prediction (Low) | - | - |
| 534 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 422 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 479 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |