Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99836 | MYD88 | Myeloid differentiation primary response protein … | Homo sapiens (Human) | 296 aa |
Protein Details: Q99836 (MYD88)
Protein Information
| Accession | Q99836 |
|---|---|
| Protein Names | Myeloid differentiation primary response protein MyD88 |
| Gene Symbol | MYD88 |
| Organism | Homo sapiens (Human) |
| Length | 296 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAGGPGAGS11AAPVSSTSSL21PLAALNMRVR31RRLSLFLNVR41TQVAADWTAL
51-10051AEEMDFEYLE61IRQLETQADP71TGRLLDAWQG81RPGASVGRLL91ELLTKLGRDD
101-150101VLLELGPSIE111EDCQKYILKQ121QQEEAEKPLQ131VAAVDSSVPR141TAELAGITTL
151-200151DDPLGHMPER161FDAFICYCPS171DIQFVQEMIR181QLEQTNYRLK191LCVSDRDVLP
201-250201GTCVWSIASE211LIEKRCRRMV221VVVSDDYLQS231KECDFQTKFA241LSLSPGAHQK
251-296251RLIPIKYKAM261KKEFPSILRF271ITVCDYTNPC281TKSWFWTRLA291KALSLP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 113 | SWISSPALM | - | - | - |
Deep-Palm: 0.97
|
| 166 | - | - | - |
Deep-Palm: 0.11
|
|
| 168 | - | - | - |
Deep-Palm: 0.13
|
|
| 192 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.84
|
|
| 203 | - | - | - |
Deep-Palm: 0.94
|
|
| 216 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.67
|
|
| 233 | - | - | - |
Deep-Palm: 0.74
|
|
| 274 | SWISSPALM | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.35
|
| 280 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 44 | R → C | 0.012195 | SNP | Missense Mutation | MESO |
| 121 | S → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 173 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 270 | Y → C | 0.007299 | SNP | Missense Mutation | READ |
| 299 | W → C | 0.002294 | SNP | Missense Mutation | OV |
| 301 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |