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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q99943 AGPAT1; G15 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) … Homo sapiens (Human) 283 aa

Protein Details: Q99943 (AGPAT1)

Protein Information
Accession Q99943
Protein Names 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15)
Gene Symbol AGPAT1; G15
Organism Homo sapiens (Human)
Length 283 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 26111759 29575903 29733200 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.617
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.617
37/46 (80.4%)
9
Jurkat T cells
Specificity: 0.150
9/25 (36.0%)
4
HAP1 cells
Specificity: 0.067
4/10 (40.0%)
4
293T cells
Specificity: 0.067
4/10 (40.0%)
3
PC3 cells
Specificity: 0.050
3/4 (75.0%)
2
DU145 cells
Specificity: 0.033
2/2 (100.0%)
1
HeLa cells
Specificity: 0.017
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDLWPGAWML11LLLLFLLLLF21LLPTLWFCSP31SAKYFFKMAF41YNGWILFLAV
51-10051LAIPVCAVRG61RNVENMKILR71LMLLHIKYLY81GIRVEVRGAH91HFPPSQPYVV
101-150101VSNHQSSLDL111LGMMEVLPGR121CVPIAKRELL131WAGSAGLACW141LAGVIFIDRK
151-200151RTGDAISVMS161EVAQTLLTQD171VRVWVFPEGT181RNHNGSMLPF191KRGAFHLAVQ
201-250201AQVPIVPIVM211SSYQDFYCKK221ERRFTSGQCQ231VRVLPPVPTE241GLTPDDVPAL
251-283251ADRVRHSMLT261VFREISTDGR271GGGDYLKKPG281GGG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
28 Prediction (Low) - -
56 Prediction (High) - -
121 Prediction (Medium) - -
139 Prediction (Low) - -
218 Prediction (Low) - -
229 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
61 R → C 0.002545 SNP Missense Mutation GBM
70 R → C 0.002506 SNP Missense Mutation COAD
120 R → C 0.002545 SNP Missense Mutation GBM
121 C → F 0.002033 SNP Missense Mutation LUSC
151 R → C 0.001887 SNP Missense Mutation UCEC
192 R → C 0.001887 SNP Missense Mutation UCEC
222 R → C 0.002506 SNP Missense Mutation COAD
223 R → C 0.002506 SNP Missense Mutation COAD
223 R → C 0.001887 SNP Missense Mutation UCEC