Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q99K30 Eps8l2 Epidermal growth factor receptor kinase … Mus musculus (Mouse) 729 aa

Protein Details: Q99K30 (Eps8l2)

Protein Information
AccessionQ99K30
Protein NamesEpidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2)
Gene SymbolEps8l2
OrganismMus musculus (Mouse)
Length729 aa
IsoformsNo isoforms
Related PMIDs 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSQSASMSCC11PGAANGSLGR21SDGVPRMSAK31DLFEQRKKYS41NSNVIMHETS
51-10051QYHVQHLATF61IMDKSEAIAS71VDDAIRKLVQ81LSSKEKVWAQ91EVLLQVNDKS
101-150101LRLLDVESQE111ELENFPLPTV121QHSQTVLNQL131RYPSVLLLVC141QDSDQNKPDI
151-200151HFFHCDEVEA161ELVQEDIESA171LADYRLGKKM181RPQTLKGHQE191KIRQRQSILP
201-250201PPQSPAPIPF211QRQPGDSPQA221KNRVGLPLPV231PFSEPGYRRR241ESQDEEPRAV
251-300251LAQRIEKETQ261ILNCTLDDIE271WFVARLQKAA281EAFKQLNQRK291KGKKKNKKGP
301-350301AEGVLTLRAR311PPSEGEFVDC321FQKTKLAINL331LAKLQKHIQN341PSAAELVHFL
351-400351FGPLDLIINT361CGSPDIARSV371SSPLLSTDAV381SFLRGHLVPK391EMTLWESLGE
401-450401TWMRPRSEWP411REPQVPLYVP421KFRSGWEPPL431DVLQEAPWEV441EGLASVPSDQ
451-500451LTPKNRLSVR461HSPKHSLSSE471SQAPEDIAPP481GSSPHANRGY491QPTPAMTKYV
501-550501KILYDFTARN511ANELSVLKDE521VLEVLEDGRQ531WWKLRNRSGQ541AGYVPCNILA
551-600551EARQEDVGAP561LEQSGQKYWG571PASPTHKLPP581IFAGNKEELI591HHMDEVNDEL
601-650601MKKISHIKTQ611PQRNFRVERS621QPVHLPLTFE631SGPDEVRAWL641EAKAFSARIV
651-700651ENLGILTGPQ661LFSLNKEELK671KVCGEEGSRV681YSQLTVQKAF691LEKQQSGSEL
701-729701EKLMSKIRRA711EDSYTSQHTS721PESEGAPHL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
9 - - -
Deep-Palm: 0.03
10 - - -
Deep-Palm: 0.04
140 - - -
Deep-Palm: 0.56
155 - - -
Deep-Palm: 0.11
264 - - -
Deep-Palm: 0.87
320 SWISSPALM DBPTM CYSMODDB EPS8 spectrin-like domain
liver (26165157)
-
Deep-Palm: 0.96
361 - - -
Deep-Palm: 0.96
546 - - -
Deep-Palm: 0.96
673 - - -
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine