Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99KI0 | Aco2 | Aconitate hydratase, mitochondrial (Aconitase) (EC … | Mus musculus (Mouse) | 780 aa |
Protein Details: Q99KI0 (Aco2)
Protein Information
| Accession | Q99KI0 |
|---|---|
| Protein Names | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
| Gene Symbol | Aco2 |
| Organism | Mus musculus (Mouse) |
| Length | 780 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29217618 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAPYSLLVTR11LQKALGVRQY21HVASVLCQRA31KVAMSHFEPS41EYIRYDLLEK
51-10051NINIVRKRLN61RPLTLSEKIV71YGHLDDPANQ81EIERGKTYLR91LRPDRVAMQD
101-150101ATAQMAMLQF111ISSGLPKVAV121PSTIHCDHLI131EAQVGGEKDL141RRAKDINQEV
151-200151YNFLATAGAK161YGVGFWRPGS171GIIHQIILEN181YAYPGVLLIG191TDSHTPNGGG
201-250201LGGICIGVGG211ADAVDVMAGI221PWELKCPKVI231GVKLTGSLSG241WTSPKDVILK
251-300251VAGILTVKGG261TGAIVEYHGP271GVDSISCTGM281ATICNMGAEI291GATTSVFPYN
301-350301HRMKKYLSKT311GRTDIANLAE321EFKDHLVPDP331GCQYDQVIEI341NLNELKPHIN
351-400351GPFTPDLAHP361VADVGTVAEK371EGWPLDIRVG381LIGSCTNSSY391EDMGRSAAVA
401-450401KQALAHGLKC411KSQFTITPGS421EQIRATIERD431GYAQILRDVG441GIVLANACGP
451-500451CIGQWDRKDI461KKGEKNTIVT471SYNRNFTGRN481DANPETHAFV491TSPEIVTALA
501-550501IAGTLKFNPE511TDFLTGKDGK521KFKLEAPDAD531ELPRSDFDPG541QDTYQHPPKD
551-600551SSGQRVDVSP561TSQRLQLLEP571FDKWDGKDLE581DLQILIKVKG591KCTTDHISAA
601-650601GPWLKFRGHL611DNISNNLLIG621AINIENGKAN631SVRNAVTQEF641GPVPDTARYY
651-700651KKHGIRWVVI661GDENYGEGSS671REHAALEPRH681LGGRAIITKS691FARIHETNLK
701-750701KQGLLPLTFA711DPSDYNKIHP721VDKLTIQGLK731DFAPGKPLKC741VIKHPNGTQE
751-780751TILLNHTFNE761TQIEWFRAGS771ALNRMKELQQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 27 | - | - | - |
Deep-Palm: 0.93
|
|
| 126 | - |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.92
|
|
| 205 | - | - | - |
Deep-Palm: 0.85
|
|
| 226 | - | - | - |
Deep-Palm: 0.96
|
|
| 277 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.29
|
|
| 284 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.35
|
|
| 332 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.66
|
|
| 385 | SWISSPALM DBPTM CYSMODDB | Aconitase family (aconitate hydratase) |
Liver
(28526873)
brain
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.96
|
| 410 | SWISSPALM DBPTM CYSMODDB | Aconitase family (aconitate hydratase) |
liver
(26165157)
brain
(39008777)
| - |
Deep-Palm: 0.97
|
| 448 | SWISSPALM DBPTM CYSMODDB | Aconitase family (aconitate hydratase) |
Brain
(34200797)
Forebrain
(28680068)
brain
(39008777)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.94
Deep-Palm: 0.96
|
| 451 | SWISSPALM DBPTM CYSMODDB | Aconitase family (aconitate hydratase) |
Brain
(34200797)
Forebrain
(28680068)
brain
(39008777)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.94
Deep-Palm: 0.87
|
| 592 | - |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.89
|
|
| 740 | - | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
6
Liver
Specificity: 0.109
6/6 (100.0%)
5
Brain
Specificity: 0.091
5/5 (100.0%)
2
Testis
Specificity: 0.036
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.018
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
41
Brain tissue (Mass)
Specificity: 0.745
41/56 (73.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.