Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q99L04 Dhrs1 Dehydrogenase/reductase SDR family member 1 … Mus musculus (Mouse) 313 aa

Protein Details: Q99L04 (Dhrs1)

Protein Information
AccessionQ99L04
Protein NamesDehydrogenase/reductase SDR family member 1 (EC 1.1.1.-) (Short chain dehydrogenase/reductase family 19C member 1) (Protein SDR19C1)
Gene SymbolDhrs1
OrganismMus musculus (Mouse)
Length313 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVAPMKGQVC11VVTGASRGIG21RGIALQLCKA31GATVYITGRH41LDTLRATAQE
51-10051AQSLGGRCVP61VVCDSSQESE71VKSLFEQVDR81EQKGRLDVLV91NNAYAGVQAI
101-150101LNTTNKSFWE111VPASIWDDIN121NVGLRGHYLC131SVYGARLMVP141AGKGLIVIVS
151-200151SPGGLQHMFN161VPYGVGKAAC171DRLAADCAHE181LRRHGVSYVS191LWPGLVQTEM
201-250201VKEFMAKEDT211PEDPLFKKMK221PDFSSAESPE231MSGKCVVALA241TDPNILNLSG
251-300251KVLPSCDLAR261RYGLKDIDGR271PVKDYFSLGY281ALSQVSSLGW291LNSFLPGFLR
301-313301VPKWVVTLYN311SKF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
10 SWISSPALM DBPTM CYSMODDB DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 NAD(P)-binding domain superfamily short chain dehydrogenase
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.93
Deep-Palm: 0.47
28 SWISSPALM DBPTM CYSMODDB DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 short chain dehydrogenase Short-chain dehydrogenase/reductase SDR NAD(P)-binding domain superfamily
Liver (28526873)
-
GPS-Palm: 0.92
Deep-Palm: 0.98
58 - - -
Deep-Palm: 0.97
63 - - -
Deep-Palm: 0.92
130 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.95
170 - - -
Deep-Palm: 0.93
177 SWISSPALM DBPTM CYSMODDB short chain dehydrogenase
Liver (28526873)
Brain (31311849)
MLE (39008777)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.93
Deep-Palm: 0.97
235 - - -
Deep-Palm: 0.93
256 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
brain (39008777)
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.97
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.207
6/6 (100.0%)
5
Brain
Specificity: 0.172
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.621
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine