Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q99L13 Hibadh 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC … Mus musculus (Mouse) 335 aa

Protein Details: Q99L13 (Hibadh)

Protein Information
AccessionQ99L13
Protein Names3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)
Gene SymbolHibadh
OrganismMus musculus (Mouse)
Length335 aa
IsoformsNo isoforms
Related PMIDs 29660268 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAASLGFRGA11ASGLWYWSGR21RRPVGSLAAV31CSRSMASKTP41VGFIGLGNMG
51-10051NPMAKNLMKH61GYPLILYDVF71PDVCKEFKEA81GEQVASSPAE91VAEKADRIIT
101-150101MLPSSMNAVE111VYSGANGILK121KVKKGSLLID131SSTIDPSVSK141ELAKEVEKMG
151-200151AVFMDAPVSG161GVGAARSGNL171TFMVGGVEDE181FAAAQELLEC191MGSNVVYCGA
201-250201VGTGQSAKIC211NNMLLAISMI221GTAEAMNLGI231RSGLDPKLLA241KILNMSSGRC
251-300251WSSDTYNPVP261GVMHGVPSSN271NYQGGFGTTL281MAKDLGLAQD291SATSTKTPIL
301-335301LGSLAHQIYR311MMCSKGYSKK321DFSSVFQYLR331EEEPF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
31 - - -
GPS-Palm: 0.95
Deep-Palm: 0.96
74 NAD binding domain of 6-phosphogluconate dehydrogenase
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.96
190 - - -
Deep-Palm: 0.96
198 - - -
Deep-Palm: 0.75
210 - - -
Deep-Palm: 0.90
250 - - -
Deep-Palm: 0.78
313 - - -
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.455
5
Liver
Specificity: 0.294
5/5 (100.0%)
4
Brain
Specificity: 0.235
4/4 (100.0%)
2
Testis
Specificity: 0.118
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.353
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine