Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99L45 | Eif2s2 | Eukaryotic translation initiation factor 2 … | Mus musculus (Mouse) | 331 aa |
Protein Details: Q99L45 (Eif2s2)
Protein Information
| Accession | Q99L45 |
|---|---|
| Protein Names | Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF2-beta) |
| Gene Symbol | Eif2s2 |
| Organism | Mus musculus (Mouse) |
| Length | 331 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGDEMIFDP11TMSKKKKKKK21KPFMLDEEGD31AQTEETQPSE41TKEVEPEPTE
51-10051EKDVDADEED61SRKKDASDDL71DDLNFFNQKK81KKKKTKKIFD91IDEAEEAIKD
101-150101VKIESDAQEP111AEPEDDLDIM121LGNKKKKKKN131VKFPEEDEIL141EKDEALEDED
151-200151SKKDDGISFS161SQTAWAGSER171DYTYEELLNR181VFNIMREKNP191DMVAGEKRKF
201-250201VMKPPQVVRV211GTKKTSFVNF221TDICKLLHRQ231PKHLLAFLLA241ELGTSGSIDG
251-300251NNQLVIKGRF261QQKQIENVLR271RYIKEYVTCH281TCRSPDTILQ291KDTRLYFLQC
301-331301ETCHSRCSVA311SIKTGFQAVT321GKRAQLRAKA331N
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 224 | SWISSPALM DBPTM CYSMODDB | Domain found in IF2B/IF5 |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.72
|
| 279 | - | - | - |
Deep-Palm: 0.18
|
|
| 282 | - | - | - |
Deep-Palm: 0.16
|
|
| 300 | - |
MLE
(39008777)
| - |
Deep-Palm: 0.48
|
|
| 303 | - |
MLE
(39008777)
| - |
Deep-Palm: 0.56
|
|
| 307 | - |
MLE
(39008777)
| - |
Deep-Palm: 0.47
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.357
5/5 (100.0%)
2
Testis
Specificity: 0.143
2/2 (100.0%)
1
Brain
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.429
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.