Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99LB2 | Dhrs4 | Dehydrogenase/reductase SDR family member 4 … | Mus musculus (Mouse) | 279 aa |
Protein Details: Q99LB2 (Dhrs4)
Protein Information
| Accession | Q99LB2 |
|---|---|
| Protein Names | Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (EC 1.1.1.300) (NADPH-dependent carbonyl reductase) (CR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (mouNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) |
| Gene Symbol | Dhrs4 |
| Organism | Mus musculus (Mouse) |
| Length | 279 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MQKAGRLLGG11WTQAWMSVRM21ASSGLTRRNP31LSNKVALVTA41STDGIGFAIA
51-10051RRLAEDGAHV61VVSSRKQQNV71DRAVATLQGE81GLSVTGIVCH91VGKAEDREKL
101-150101ITTALKRHQG111IDILVSNAAV121NPFFGNLMDV131TEEVWDKVLS141INVTATAMMI
151-200151KAVVPEMEKR161GGGSVVIVGS171VAGFTRFPSL181GPYNVSKTAL191LGLTKNFAAE
201-250201LAPKNIRVNC211LAPGLIKTRF221SSVLWEEKAR231EDFIKEAMQI241RRLGKPEDCA
251-279251GIVSFLCSED261ASYINGETVV271VGGGTPSRL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 89 | SWISSPALM DBPTM CYSMODDB | - | - |
Brain
(35358180)
|
Deep-Palm: 0.98
|
| 210 | Enoyl-(Acyl carrier protein) reductase |
Liver
(28526873)
| - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
|
| 249 | - | - | - |
Deep-Palm: 0.94
|
|
| 257 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.462
6/6 (100.0%)
3
Brain
Specificity: 0.231
3/3 (100.0%)
2
Testis
Specificity: 0.154
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Brain tissue (Mass)
Specificity: 0.154
2/56 (3.6%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.