Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q99LF4 Rtcb RNA-splicing ligase RTCB (EC 6.5.1.8) … Mus musculus (Mouse) 505 aa

Protein Details: Q99LF4 (Rtcb)

Protein Information
AccessionQ99LF4
Protein NamesRNA-splicing ligase RTCB (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) (Focal adhesion-associated protein) (FAAP) (RNA 2',3'-cyclic phosphate and 5'-OH ligase)
Gene SymbolRtcb
OrganismMus musculus (Mouse)
Length505 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRNYNDELQ11FLDKINKNCW21RIKKGFVPNM31QVEGVFYVND41ALEKLMFEEL
51-10051RNACRGGGVG61GFLPAMKQIG71NVAALPGIVH81RSIGLPDVHS91GYGFAIGNMA
101-150101AFDMNDPEAV111VSPGGVGFDI121NCGVRLLRTN131LDESDVQPVK141EQLAQAMFDH
151-200151IPVGVGSKGV161IPMNAKDLEE171ALEMGVDWSL181REGYAWAEDK191EHCEEYGRML
201-250201QADPNKVSPR211AKKRGLPQLG221TLGAGNHYAE231IQVVDEIFNE241YAAKKMGIDH
251-300251KGQVCVMIHS261GSRGLGHQVA271TDALVAMEKA281MKRDKIIVND291RQLACARIAS
301-350301PEGQDYLKGM311AAAGNYAWVN321RSSMTFLTRQ331AFAKVFNTTP341DDLDLHVIYD
351-400351VSHNIAKVEQ361HVVDGKERTL371LVHRKGSTRA381FPPHHPLIAV391DYQLTGQPVL
401-450401IGGTMGTCSY411VLTGTEQGMT421ETFGTTCHGA431GRALSRAKSR441RNLDFQDVLD
451-500451KLADMGIAIR461VASPKLVMEE471APESYKNVTD481VVNTCHDAGI491SKKAIKLRPI
501-505501AVIKG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
19 - - -
Deep-Palm: 0.13
54 - - -
Deep-Palm: 0.96
122 - - -
Deep-Palm: 0.94
193 - - -
Deep-Palm: 0.51
255 - - -
Deep-Palm: 0.65
295 - - -
Deep-Palm: 0.90
408 - - -
Deep-Palm: 0.85
427 - - -
Deep-Palm: 0.93
485 SWISSPALM DBPTM CYSMODDB tRNA-splicing ligase RtcB
Liver (28526873)
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.89
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
6
Liver
Specificity: 0.375
6/6 (100.0%)
2
Brain
Specificity: 0.125
2/2 (100.0%)
2
Testis
Specificity: 0.125
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.375
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine