Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99MR8 | Mccc1 | Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial … | Mus musculus (Mouse) | 717 aa |
Protein Details: Q99MR8 (Mccc1)
Protein Information
| Accession | Q99MR8 |
|---|---|
| Protein Names | Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) |
| Gene Symbol | Mccc1 |
| Organism | Mus musculus (Mouse) |
| Length | 717 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAAALLAAV11DRNQLRRVPI21LLLQPREWAW31KLRTMKYGTT41PGGSITKVLI
51-10051ANRGEIACRV61IRTAKKMGVQ71SVAVYSEADR81NSMHVDMADE91AYSIGPAPSQ
101-150101QSYLAMEKII111QVAKSSAAQA121IHPGYGFLSE131NMEFAELCKQ141EGIIFIGPPS
151-200151SAIRDMGIKS161TSKSIMAAAG171VPVVEGYHGK181DQSDQCLREH191AGKIGYPVMI
201-250201KAVRGGGGKG211MRIVRSEREF221QEQLESARRE231AKKSFNDDAM241LIEKFVDTPR
251-300251HVEVQVFGDH261HGNAVYLFER271DCSVQRRHQK281IIEEAPAPGI291NPEVRRKLGE
301-350301AAVRAAKAVK311YVGAGTVEFI321MDSRHNFYFM331EMNTRLQVEH341PVTEMITGTD
351-400351LVEWQLRIAA361GEKIPLSQEE371IPLQGHAFEA381RIYAEDPDNN391FMPGAGPLVH
401-450401LSTPSADMST411RIETGVRQGD421EVSVHYDPMI431AKLVVWASDR441QSALSKLRYC
451-500451LHQYNIVGLR461SNVDFLLRLS471GHPEFEAGNV481HTDFIPQHHK491DLLPSHSTIA
501-550501KESVCQAALG511LILKEKEMTS521AFKLHTQDQF531SPFSFSSGRR541LNISYTRNMT
551-600551LRSGKSDIVI561AVTYNRDGSY571DMQIDNKSFR581VLGDLSSEDG591CTYLKSSING
601-650601VARKSKFILL611DNTVHLFSME621GSIEVGIPVP631KYLSPVSAEG641AQGGTIAPMT
651-700651GTIEKVFVKA661GDRVKAGDSL671MVMIAMKMEH681TIKAPKDGRI691KKVFFSEGAQ
701-717701ANRHAPLVEF711EEEESDK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 58 | SWISSPALM DBPTM CYSMODDB | Biotin carboxylase, N-terminal domain |
liver
(26165157)
| - |
GPS-Palm: 0.94
Deep-Palm: 0.96
|
| 138 | - | - | - |
Deep-Palm: 0.88
|
|
| 186 | Carbamoyl-phosphate synthase L chain ATP binding domain |
Brain
(34200797)
| - |
Deep-Palm: 0.89
|
|
| 272 | - | - | - |
Deep-Palm: 0.59
|
|
| 450 | - | - | - |
Deep-Palm: 0.89
|
|
| 505 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
liver
(26165157)
|
Brain
(35358180)
Macrophage Raw 264.7
(29217618)
Brain
(31311849)
|
GPS-Palm: 0.91
Deep-Palm: 0.97
|
| 591 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.455
5
Liver
Specificity: 0.132
5/5 (100.0%)
4
Brain
Specificity: 0.105
4/4 (100.0%)
2
Testis
Specificity: 0.053
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
18
Brain tissue (Mass)
Specificity: 0.474
18/56 (32.1%)
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.237
9/10 (90.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.