Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q99MX7 | Tmem121b | Transmembrane protein 121B (Cat eye … | Mus musculus (Mouse) | 572 aa |
Protein Details: Q99MX7 (Tmem121b)
Protein Information
| Accession | Q99MX7 |
|---|---|
| Protein Names | Transmembrane protein 121B (Cat eye syndrome critical region protein 6 homolog) |
| Gene Symbol | Tmem121b |
| Organism | Mus musculus (Mouse) |
| Length | 572 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31311849 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MHPALGHPRA11LSSAPASFPP21PPAAARLQPL31FLRGGSSRGR41RGSGDSSTST
51-10051STSRGGCGGR61RGGGGGSPSS71STGAEREDDD81ESISISKPLV91PAAAALPGPP
101-150101AQGGVPVSAT111APAAASSTST121PTSSCSMTAA131DFGAGAAAGT141VGGPGSRSAV
151-200151GAGGTGTGGA161ASCCSCCCCC171CGRPTRSGRR181GRRRGCSPSP191GCRWGYQALS
201-250201VVLLLAQGGL211LDLYLIAVTD221LYWCSWIATD231LVVVVGWAIF241FAKNSRGRRG
251-300251GPANSMHNHH261QLHHHSAPPL271HLSAAASAGA281GAKARGGRGG291SGGSGAGPGT
301-350301TGAAGEFAFA311YLAWLIYSIA321FTPKVVLILG331TSILDLIELR341APFGTTGFRL
351-400351TMALSVPLLY361SLVRAISEAG371APPGSAGPLL381LQPQQHRAAG391CFLGTCLDLL
401-450401DSFTLVELML411DGRVPLPAHL421RYLLIAVYFL431TLASPVLWLY441ELNTATAAPS
451-500451WGQTSGPGSC461SRLLRLLGGC471LVDVPLLALR481SLLVVSYQQP491LSIFMLKNLF
501-550501FLGCRGLEAL511EGCWDRGSWV521SPSRARSSYG531APPSAPPPPP541PPPPQGGSQR
551-572551GHLENEGGPH561GYVNTLAVAS571QN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 57 | - | - | - |
Deep-Palm: 0.93
|
|
| 125 | - | - | - |
Deep-Palm: 0.95
|
|
| 163 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.65
|
|
| 164 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.69
|
|
| 166 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.73
|
|
| 167 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.66
|
|
| 168 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.60
|
|
| 169 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.57
|
|
| 170 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.63
|
|
| 171 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.56
|
|
| 186 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.92
|
|
| 192 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.98
|
|
| 224 | - | - | - |
Deep-Palm: 0.79
|
|
| 391 | - | - | - |
Deep-Palm: 0.97
|
|
| 396 | - | - | - |
Deep-Palm: 0.94
|
|
| 460 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.98
|
|
| 470 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.91
Deep-Palm: 0.99
|
|
| 504 | SWISSPALM DBPTM CYSMODDB | CECR6/TMEM121 family |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.88
Deep-Palm: 0.94
|
| 513 | SWISSPALM DBPTM CYSMODDB | - |
Brain
(31311849)
Forebrain
(28680068)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Brain
Specificity: 0.083
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
22
Brain tissue (Mass)
Specificity: 0.917
22/56 (39.3%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.