Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9BQ39 DDX50 ATP-dependent RNA helicase DDX50 (EC … Homo sapiens (Human) 737 aa

Protein Details: Q9BQ39 (DDX50)

Protein Information
Accession Q9BQ39
Protein Names ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene Symbol DDX50
Organism Homo sapiens (Human)
Length 737 aa
Isoforms No isoforms
Related PMIDs 29575903 29733200 31251020 31382980
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.793
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
23
LNCaP cells
Specificity: 0.793
23/46 (50.0%)
4
HAP1 cells
Specificity: 0.138
4/10 (40.0%)
1
U937 cells
Specificity: 0.034
1/1 (100.0%)
1
HeLa cells
Specificity: 0.034
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPGKLLWGDI11MELEAPLEES21ESQKKERQKS31DRRKSRHHYD41SDEKSETREN
51-10051GVTDDLDAPK61AKKSKMKEKL71NGDTEEGFNR81LSDEFSKSHK91SRRKDLPNGD
101-150101IDEYEKKSKR111VSSLDTSTHK121SSDNKLEETL131TREQKEGAFS141NFPISEETIK
151-200151LLKGRGVTYL161FPIQVKTFGP171VYEGKDLIAQ181ARTGTGKTFS191FAIPLIERLQ
201-250201RNQETIKKSR211SPKVLVLAPT221RELANQVAKD231FKDITRKLSV241ACFYGGTSYQ
251-300251SQINHIRNGI261DILVGTPGRI271KDHLQSGRLD281LSKLRHVVLD291EVDQMLDLGF
301-350301AEQVEDIIHE311SYKTDSEDNP321QTLLFSATCP331QWVYKVAKKY341MKSRYEQVDL
351-400351VGKMTQKAAT361TVEHLAIQCH371WSQRPAVIGD381VLQVYSGSEG391RAIIFCETKK
401-450401NVTEMAMNPH411IKQNAQCLHG421DIAQSQREIT431LKGFREGSFK441VLVATNVAAR
451-500451GLDIPEVDLV461IQSSPPQDVE471SYIHRSGRTG481RAGRTGICIC491FYQPRERGQL
501-550501RYVEQKAGIT511FKRVGVPSTM521DLVKSKSMDA531IRSLASVSYA541AVDFFRPSAQ
551-600551RLIEEKGAVD561ALAAALAHIS571GASSFEPRSL581ITSDKGFVTM591TLESLEEIQD
601-650601VSCAWKELNR611KLSSNAVSQI621TRMCLLKGNM631GVCFDVPTTE641SERLQAEWHD
651-700651SDWILSVPAK661LPEIEEYYDG671NTSSNSRQRS681GWSSGRSGRS691GRSGGRSGGR
701-737701SGRQSRQGSR711SGSRQDGRRR721SGNRNRSRSG731GHKRSFD
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
242 Prediction (Low) - -
329 Prediction (Low) - -
417 Prediction (Low) - -
488 Prediction (High) - -
490 Prediction (High) - -
603 Prediction (Low) - -
624 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
269 R → C 0.005618 SNP Missense Mutation PAAD
450 R → C 0.002747 SNP Missense Mutation LIHC
513 R → C 0.015152 SNP Missense Mutation KICH
717 G → C 0.002747 SNP Missense Mutation LIHC
720 R → Cfs*31 0.002506 INS Frame Shift Ins COAD
? ? → ? 0.002747 SNP Missense Mutation LIHC