Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9BR39 JPH2 Junctophilin-2 (JP-2) (Junctophilin type 2) … Homo sapiens (Human) 696 aa

Protein Details: Q9BR39 (JPH2)

Protein Information
AccessionQ9BR39
Protein NamesJunctophilin-2 (JP-2) (Junctophilin type 2) [Cleaved into: Junctophilin-2 N-terminal fragment (JP2NT)]
Gene SymbolJPH2
OrganismHomo sapiens (Human)
Length696 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGGRFDFDD11GGAYCGGWEG21GKAHGHGLCT31GPKGQGEYSG41SWNFGFEVAG
51-10051VYTWPSGNTF61EGYWSQGKRH71GLGIETKGRW81LYKGEWTHGF91KGRYGIRQSS
101-150101SSGAKYEGTW111NNGLQDGYGT121ETYADGGTYQ131GQFTNGMRHG141YGVRQSVPYG
151-200151MAVVVRSPLR161TSLSSLRSEH171SNGTVAPDSP181ASPASDGPAL191PSPAIPRGGF
201-250201ALSLLANAEA211AARAPKGGGL221FQRGALLGKL231RRAESRTSVG241SQRSRVSFLK
251-300251SDLSSGASDA261ASTASLGEAA271EGADEAAPFE281ADIDATTTET291YMGEWKNDKR
301-350301SGFGVSERSS311GLRYEGEWLD321NLRHGYGCTT331LPDGHREEGK341YRHNVLVKDT
351-400351KRRMLQLKSN361KVRQKVEHSV371EGAQRAAAIA381RQKAEIAASR391TSHAKAKAEA
401-450401AEQAALAANQ411ESNIARTLAR421ELAPDFYQPG431PEYQKRRLLQ441EILENSESLL
451-500451EPPDRGAGAA461GLPQPPRESP471QLHERETPRP481EGGSPSPAGT491PPQPKRPRPG
501-550501VSKDGLLSPG511AWNGEPSGEG521SRSVTPSEGA531GRRSPARPAT541ERMAIEALQA
551-600551PPAPSREPEV561ALYQGYHSYA571VRTTPPEPPP581FEDQPEPEVS591GSESAPSSPA
601-650601TAPLQAPTLR611GPEPARETPA621KLEPKPIIPK631AEPRAKARKT641EARGLTKAGA
651-696651KKKARKEAAL661AAEAEVEVEE671VPNTILICMV681ILLNIGLAIL691FVHLLT
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
15 SWISSPALM Junctophilin MORN repeat Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain - -
Deep-Palm: 0.54
29 SWISSPALM Junctophilin MORN repeat Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain - -
GPS-Palm: 0.76
Deep-Palm: 0.85
328 SWISSPALM MORN repeat - -
Deep-Palm: 0.77
678 SWISSPALM - - -
GPS-Palm: 0.65
Deep-Palm: 0.74
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
15 C → G 0.002294 SNP Missense Mutation OV
17 G → C 0.001764 SNP Missense Mutation LUAD
41 S → C 0.001969 SNP Missense Mutation HNSC
79 R → C 0.002288 SNP Missense Mutation STAD
93 R → C 0.010870 SNP Missense Mutation ACC
144 R → C 0.002506 SNP Missense Mutation COAD
144 R → C 0.005435 SNP Missense Mutation ESCA
160 R → C 0.001887 SNP Missense Mutation UCEC
236 R → C 0.002747 SNP Missense Mutation LIHC
300 R → C 0.012500 SNP Missense Mutation UVM
308 R → C 0.002545 SNP Missense Mutation GBM
381 R → C 0.002506 SNP Missense Mutation COAD
537 R → C 0.002288 SNP Missense Mutation STAD
572 R → C 0.002288 SNP Missense Mutation STAD