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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9BRT2 UQCC2; C6orf125; MNF1 Ubiquinol-cytochrome c reductase complex assembly … Homo sapiens (Human) 126 aa

Protein Details: Q9BRT2 (UQCC2)

Protein Information
Accession Q9BRT2
Protein Names Ubiquinol-cytochrome c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19)
Gene Symbol UQCC2; C6orf125; MNF1
Organism Homo sapiens (Human)
Length 126 aa
Isoforms No isoforms
Related PMIDs 19801377 22496122 24357059 26111759 29733200 31251020 32651440 32944167 33636221 36430497
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.552
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.552
37/46 (80.4%)
7
Jurkat T cells
Specificity: 0.104
7/25 (28.0%)
4
HAP1 cells
Specificity: 0.060
4/10 (40.0%)
4
293T cells
Specificity: 0.060
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.060
4/4 (100.0%)
3
PC3 cells
Specificity: 0.045
3/4 (75.0%)
3
T cells
Specificity: 0.045
3/4 (75.0%)
2
DU145 cells
Specificity: 0.030
2/2 (100.0%)
2
Endothelial cells
Specificity: 0.030
2/2 (100.0%)
1
Liver membrane
Specificity: 0.015
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAASRYRRFL11KLCEEWPVDE21TKRGRDLGAY31LRQRVAQAFR41EGENTQVAEP
51-10051EACDQMYESL61ARLHSNYYKH71KYPRPRDTSF81SGLSLEEYKL91ILSTDTLEEL
101-126101KEIDKGMWKK111LQEKFAPKGP121EEDHKA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
13 Prediction (High) - -
53 Experimental DBPTM SWISSPALM Complex III assembly factor UQCC2/CBP6 19801377
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
53 C → C 0.002288 SNP Silent STAD
67 Y → C 0.007299 SNP Missense Mutation READ
74 R → C 0.002427 SNP Missense Mutation BLCA