Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9BRT2 | UQCC2 | Ubiquinol-cytochrome c reductase complex assembly … | Homo sapiens (Human) | 126 aa |
Protein Details: Q9BRT2 (UQCC2)
Protein Information
| Accession | Q9BRT2 |
|---|---|
| Protein Names | Ubiquinol-cytochrome c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) |
| Gene Symbol | UQCC2 |
| Organism | Homo sapiens (Human) |
| Length | 126 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 26111759 29733200 31251020 32651440 32944167 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAASRYRRFL11KLCEEWPVDE21TKRGRDLGAY31LRQRVAQAFR41EGENTQVAEP
51-10051EACDQMYESL61ARLHSNYYKH71KYPRPRDTSF81SGLSLEEYKL91ILSTDTLEEL
101-126101KEIDKGMWKK111LQEKFAPKGP121EEDHKA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | Complex III assembly factor UQCC2/CBP6 Ubiquinol-cytochrome-c reductase complex assembly factor 2 | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.94
Deep-Palm: 0.97
|
|
| 53 | DBPTM SWISSPALM | Complex III assembly factor UQCC2/CBP6 | - | - |
Deep-Palm: 0.69
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.280
7
Jurkat T cell
Specificity: 0.226
7/7 (100.0%)
4
LNCaP
Specificity: 0.129
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.129
4/4 (100.0%)
3
Primary T cell
Specificity: 0.097
3/3 (100.0%)
3
PC3
Specificity: 0.097
3/3 (100.0%)
1
HAP1 cell
Specificity: 0.032
1/1 (100.0%)
1
EC cell
Specificity: 0.032
1/1 (100.0%)
1
heart
Specificity: 0.032
1/1 (100.0%)
1
HUVECs
Specificity: 0.032
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Cerebral Cortex (Mass)
Specificity: 0.129
4/4 (100.0%)
2
LNCaP cells (Mass)
Specificity: 0.065
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 53 | C → C | 0.002288 | SNP | Silent | STAD |
| 67 | Y → C | 0.007299 | SNP | Missense Mutation | READ |
| 74 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |