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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9BS26 ERP44 Endoplasmic reticulum resident protein 44 … Homo sapiens (Human) 406 aa

Protein Details: Q9BS26 (ERP44)

Protein Information
AccessionQ9BS26
Protein NamesEndoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)
Gene SymbolERP44
OrganismHomo sapiens (Human)
Length406 aa
IsoformsNo isoforms
Related PMIDs 24357059 31251020 33636221 36430497
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MHPAVFLSLP11DLRCSLLLLV21TWVFTPVTTE31ITSLDTENID41EILNNADVAL
51-10051VNFYADWCRF61SQMLHPIFEE71ASDVIKEEFP81NENQVVFARV91DCDQHSDIAQ
101-150101RYRISKYPTL111KLFRNGMMMK121REYRGQRSVK131ALADYIRQQK141SDPIQEIRDL
151-200151AEITTLDRSK161RNIIGYFEQK171DSDNYRVFER181VANILHDDCA191FLSAFGDVSK
201-250201PERYSGDNII211YKPPGHSAPD221MVYLGAMTNF231DVTYNWIQDK241CVPLVREITF
251-300251ENGEELTEEG261LPFLILFHMK271EDTESLEIFQ281NEVARQLISE291KGTINFLHAD
301-350301CDKFRHPLLH311IQKTPADCPV321IAIDSFRHMY331VFGDFKDVLI341PGKLKQFVFD
351-400351LHSGKLHREF361HHGPDPTDTA371PGEQAQDVAS381SPPESSFQKL391APSEYRYTLL
401-406401RDRDEL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
14 - - -
GPS-Palm: 0.71
Deep-Palm: 0.92
58 - - -
GPS-Palm: 0.69
Deep-Palm: 0.12
92 - - -
Deep-Palm: 0.63
189 - - -
GPS-Palm: 0.77
Deep-Palm: 0.80
241 - - -
Deep-Palm: 0.23
301 - - -
Deep-Palm: 0.64
318 - - -
GPS-Palm: 0.77
Deep-Palm: 0.38
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
1
heart
Specificity: 0.125
1/1 (100.0%)
1
HUVECs
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
102 Y → C 0.001887 SNP Missense Mutation UCEC
114 R → C 0.002506 SNP Missense Mutation COAD
195 F → C 0.001887 SNP Missense Mutation UCEC