Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9BUF5 | TUBB6 | Tubulin beta-6 chain (Tubulin beta … | Homo sapiens (Human) | 446 aa |
Protein Details: Q9BUF5 (TUBB6)
Protein Information
| Accession | Q9BUF5 |
|---|---|
| Protein Names | Tubulin beta-6 chain (Tubulin beta class V) |
| Gene Symbol | TUBB6 |
| Organism | Homo sapiens (Human) |
| Length | 446 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 29733200 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
6
HAP1 cells
Specificity: 0.500
6/10 (60.0%)
4
Jurkat T cells
Specificity: 0.333
4/25 (16.0%)
1
U937 cells
Specificity: 0.083
1/1 (100.0%)
1
PC3 cells
Specificity: 0.083
1/4 (25.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREIVHIQAG11QCGNQIGTKF21WEVISDEHGI31DPAGGYVGDS41ALQLERINVY
51-10051YNESSSQKYV61PRAALVDLEP71GTMDSVRSGP81FGQLFRPDNF91IFGQTGAGNN
101-150101WAKGHYTEGA111ELVDAVLDVV121RKECEHCDCL131QGFQLTHSLG141GGTGSGMGTL
151-200151LISKIREEFP161DRIMNTFSVM171PSPKVSDTVV181EPYNATLSVH191QLVENTDETY
201-250201CIDNEALYDI211CFRTLKLTTP221TYGDLNHLVS231ATMSGVTTSL241RFPGQLNADL
251-300251RKLAVNMVPF261PRLHFFMPGF271APLTSRGSQQ281YRALTVPELT291QQMFDARNMM
301-350301AACDPRHGRY311LTVATVFRGP321MSMKEVDEQM331LAIQSKNSSY341FVEWIPNNVK
351-400351VAVCDIPPRG361LKMASTFIGN371STAIQELFKR381ISEQFSAMFR391RKAFLHWFTG
401-446401EGMDEMEFTE411AESNMNDLVS421EYQQYQDATA431NDGEEAFEDE441EEEIDG
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 211 | Prediction (Medium) | - | - |
| 303 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Tubulin C-terminal domain | - |
| 354 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 146 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 153 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 201 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 241 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 244 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 251 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 303 | C → C | 0.001887 | SNP | Silent | UCEC |
| 318 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |