Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9BUM1 | G6PC3; UGRP | Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase … | Homo sapiens (Human) | 346 aa |
Protein Details: Q9BUM1 (G6PC3)
Protein Information
| Accession | Q9BUM1 |
|---|---|
| Protein Names | Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9) (Glucose-6-phosphatase beta) (G6Pase-beta) (Ubiquitous glucose-6-phosphatase catalytic subunit-related protein) |
| Gene Symbol | G6PC3; UGRP |
| Organism | Homo sapiens (Human) |
| Length | 346 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.933
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
14
LNCaP cells
Specificity: 0.933
14/46 (30.4%)
1
Cerebral cortex
Specificity: 0.067
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MESTLGAGIV11IAEALQNQLA21WLENVWLWIT31FLGDPKILFL41FYFPAAYYAS
51-10051RRVGIAVLWI61SLITEWLNLI71FKWFLFGDRP81FWWVHESGYY91SQAPAQVHQF
101-150101PSSCETGPGS111PSGHCMITGA121ALWPIMTALS131SQVATRARSR141WVRVMPSLAY
151-200151CTFLLAVGLS161RIFILAHFPH171QVLAGLITGA181VLGWLMTPRV191PMERELSFYG
201-250201LTALALMLGT211SLIYWTLFTL221GLDLSWSISL231AFKWCERPEW241IHVDSRPFAS
251-300251LSRDSGAALG261LGIALHSPCY271AQVRRAQLGN281GQKIACLVLA291MGLLGPLDWL
301-346301GHPPQISLFY311IFNFLKYTLW321PCLVLALVPW331AVHMFSAQEA341PPIHSS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 151 | Prediction (Low) | - | - |
| 269 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 19801377 |
| 286 | Prediction (Medium) | - | - |
| 322 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 26 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 66 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 274 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |