Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9BUM1 | G6PC3 | Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase … | Homo sapiens (Human) | 346 aa |
Protein Details: Q9BUM1 (G6PC3)
Protein Information
| Accession | Q9BUM1 |
|---|---|
| Protein Names | Glucose-6-phosphatase 3 (G-6-Pase 3) (G6Pase 3) (EC 3.1.3.9) (Glucose-6-phosphatase beta) (G6Pase-beta) (Ubiquitous glucose-6-phosphatase catalytic subunit-related protein) |
| Gene Symbol | G6PC3 |
| Organism | Homo sapiens (Human) |
| Length | 346 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MESTLGAGIV11IAEALQNQLA21WLENVWLWIT31FLGDPKILFL41FYFPAAYYAS
51-10051RRVGIAVLWI61SLITEWLNLI71FKWFLFGDRP81FWWVHESGYY91SQAPAQVHQF
101-150101PSSCETGPGS111PSGHCMITGA121ALWPIMTALS131SQVATRARSR141WVRVMPSLAY
151-200151CTFLLAVGLS161RIFILAHFPH171QVLAGLITGA181VLGWLMTPRV191PMERELSFYG
201-250201LTALALMLGT211SLIYWTLFTL221GLDLSWSISL231AFKWCERPEW241IHVDSRPFAS
251-300251LSRDSGAALG261LGIALHSPCY271AQVRRAQLGN281GQKIACLVLA291MGLLGPLDWL
301-346301GHPPQISLFY311IFNFLKYTLW321PCLVLALVPW331AVHMFSAQEA341PPIHSS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 104 | - | - | - |
Deep-Palm: 0.06
|
|
| 115 | - | - | - |
Deep-Palm: 0.11
|
|
| 151 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.96
|
|
| 235 | - | - | - |
Deep-Palm: 0.89
|
|
| 269 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.91
Deep-Palm: 0.96
|
| 286 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.98
|
|
| 322 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.23
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 0.500
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP cells (Mass)
Specificity: 0.250
1/4 (25.0%)
1
Cerebral Cortex (Mass)
Specificity: 0.250
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 26 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 66 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 274 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |