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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9BVA1 TUBB2B Tubulin beta-2B chain Homo sapiens (Human) 445 aa

Protein Details: Q9BVA1 (TUBB2B)

Protein Information
Accession Q9BVA1
Protein Names Tubulin beta-2B chain
Gene Symbol TUBB2B
Organism Homo sapiens (Human)
Length 445 aa
Isoforms No isoforms
Related PMIDs 21076176 29733200 31251020 36430497 37611173
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.632
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.632
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.175
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.105
6/25 (24.0%)
4
293T cells
Specificity: 0.070
4/10 (40.0%)
1
Cerebral cortex
Specificity: 0.018
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREIVHIQAG11QCGNQIGAKF21WEVISDEHGI31DPTGSYHGDS41DLQLERINVY
51-10051YNEATGNKYV61PRAILVDLEP71GTMDSVRSGP81FGQIFRPDNF91VFGQSGAGNN
101-150101WAKGHYTEGA111ELVDSVLDVV121RKESESCDCL131QGFQLTHSLG141GGTGSGMGTL
151-200151LISKIREEYP161DRIMNTFSVM171PSPKVSDTVV181EPYNATLSVH191QLVENTDETY
201-250201CIDNEALYDI211CFRTLKLTTP221TYGDLNHLVS231ATMSGVTTCL241RFPGQLNADL
251-300251RKLAVNMVPF261PRLHFFMPGF271APLTSRGSQQ281YRALTVPELT291QQMFDSKNMM
301-350301AACDPRHGRY311LTVAAIFRGR321MSMKEVDEQM331LNVQNKNSSY341FVEWIPNNVK
351-400351TAVCDIPPRG361LKMSATFIGN371STAIQELFKR381ISEQFTAMFR391RKAFLHWYTG
401-445401EGMDEMEFTE411AESNMNDLVS421EYQQYQDATA431DEQGEFEEEE441GEDEA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
12 CYSMODDB SWISSPALM DBPTM Tubulin/FtsZ family GTPase domain -
211 Prediction (Medium) - -
239 Prediction (High) - -
303 Prediction (High) - -
354 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Tubulin C-terminal domain 37611173
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
13 G → C 0.002747 SNP Missense Mutation LIHC
21 W → C 0.002294 SNP Missense Mutation OV
162 R → C 0.002506 SNP Missense Mutation COAD
162 R → C 0.001887 SNP Missense Mutation UCEC
211 C → C 0.002427 SNP Silent BLCA
251 R → C 0.001887 SNP Missense Mutation UCEC
262 R → C 0.001887 SNP Missense Mutation UCEC
391 R → C 0.002288 SNP Missense Mutation STAD