Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q9C0C2-2 | TNKS1BP1 | 182 kDa tankyrase-1-binding protein | Homo sapiens (Human) | 778 aa |
Protein Details: Q9C0C2-2 (TNKS1BP1)
Protein Information
| Accession | Q9C0C2-2 |
|---|---|
| Protein Names | 182 kDa tankyrase-1-binding protein |
| Gene Symbol | TNKS1BP1 |
| Organism | Homo sapiens (Human) |
| Length | 778 aa |
| Isoforms | |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSLTQKGDGE11SQPQFPAVPL21EPLPTTEGTP31GLPLQQAEER41YESQEPLAGQ
51-10051ESPLPLATRE61AALPILEPVL71GQEQPAAPDQ81PCVLFADAPE91PGQALPVEEE
101-150101AVTLARAETT111QARTEAQDLC121RASPEPPGPE131SSSRWLDDLL141ASPPPSGGGA
151-200151RRGAGAELKD161TQSPSTCSEG171LLGWSQKDLQ181SEFGITGDPQ191PSSFSPSSWC
201-250201QGASQDYGLG211GASPRGDPGL221GERDWTSKYG231QGAGEGSTRE241WASRCGIGQE
251-300251EMEASSSQDQ261SKVSAPGVLT271AQDRVVGKPA281QLGTQRSQEA291DVQDWEFRKR
301-350301DSQGTYSSRD311AELQDQEFGK321RDSLGTYSSR331DVSLGDWEFG341KRDSLGAYAS
351-400351QDANEQGQDL361GKRDHHGRYS371SQDADEQDWE381FQKRDVSLGT391YGSRAAEPQE
401-450401QEFGKSAWIR411DYSSGGSSRT421LDAQDRSFGT431RPLSSGFSPE441EAQQQDEEFE
451-500451KKIPSVEDSL461GEGSRDAGRP471GERGSGGLFS481PSTAHVPDGA491LGQRDQSSWQ
501-550501NSDASQEVGG511HQERQQAGAQ521GPGSADLEDG531EMGKRGWVGE541FSLSVGPQRE
551-600551AAFSPGQQDW561SRDFCIEASE571RSYQFGIIGN581DRVSGAGFSP591SSKMEGGHFV
601-650601PPGKTTAGSV611DWTDQLGLRN621LEVSSCVGSG631GSSEARESAV641GQMGWSGGLS
651-700651LRDMNLTGCL661ESGGSEEPGG671IGVGEKDWTS681DVNVKSKDLA691EVGEGGGHSQ
701-750701ARESGVGQTD711WSGVEAGEFL721KSRERLGRHI731YALCITLRTP741PTPSLPWISS
751-778751LVVEGFVPSS761PPSLSLSASS771SSLPWVFF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 136 | - | - | - |
Deep-Palm: 0.96
|
|
| 232 | - | - | - |
Deep-Palm: 0.87
|
|
| 313 | - | - | - |
Deep-Palm: 0.75
|
|
| 331 | - | - | - |
Deep-Palm: 0.96
|
|
| 631 | - | - | - |
Deep-Palm: 0.92
|
|
| 669 | - | - | - |
Deep-Palm: 0.95
|
|
| 716 | - | - | - |
Deep-Palm: 0.96
|
|
| 734 | - | - | - |
GPS-Palm: 0.92
|
|
| 749 | - | - | - |
Deep-Palm: 0.83
|
|
| 794 | - | - | - |
Deep-Palm: 0.79
|
|
| 1114 | - | - | - |
Deep-Palm: 0.35
|
|
| 1175 | - | - | - |
Deep-Palm: 0.96
|
|
| 1208 | - | - | - |
Deep-Palm: 0.96
|
|
| 1296 | - | - | - |
Deep-Palm: 0.91
|
|
| 1324 | - | - | - |
Deep-Palm: 0.83
|
|
| 1337 | - | - | - |
Deep-Palm: 0.64
|
|
| 1373 | - | - | - |
Deep-Palm: 0.91
|
|
| 1443 | - | - | - |
Deep-Palm: 0.97
|
|
| 1690 | - | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 150 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 181 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 462 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 490 | W → C | 0.002506 | SNP | Missense Mutation | COAD |
| 577 | G → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 751 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 813 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 1114 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 1140 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 1178 | S → C | 0.002288 | SNP | Missense Mutation | STAD |
| 1229 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 1262 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 1507 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 1592 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |