Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9CZN7 Shmt2 Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC … Mus musculus (Mouse) 504 aa

Protein Details: Q9CZN7 (Shmt2)

Protein Information
AccessionQ9CZN7
Protein NamesSerine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
Gene SymbolShmt2
OrganismMus musculus (Mouse)
Length504 aa
IsoformsNo isoforms
Related PMIDs 34884899 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVSFSLLRTT11RPLQRCGQLV21CMAARAQHSK31VAQTQAGEAA41GGWTGQESLS
51-10051DSDPEMWELL61QREKDRQCRG71LELIASENFC81SRAALEALGS91CLNNKYSEGY
101-150101PGKRYYGGAE111VVDEIELLCQ121RRALEAFDLD131PAQWGVNVQP141YSGSPANLAA
151-200151YTALLQPHDR161IMGLDLPDGG171HLTHGYMSDV181KRISATSIFF191ESMPYKLNPQ
201-250201TGLIDYDQLA211LTARLFRPRL221IIAGTSAYAR231LIDYARMREV241CDEVRAHLLA
251-300251DMAHISGLVA261AKVIPSPFKY271ADVVTTTTHK281TLRGARSGLI291FYRKGVRTVD
301-350301PKTGKEIPYT311FEDRINFAVF321PSLQGGPHNH331AIAAVAVALK341QACTPMFREY
351-400351SLQVLRNAQA361MADALLKRGY371SLVSGGTDTH381LVLVDLRPKG391LDGARAERVL
401-450401ELVSITANKN411TCPGDRSAIT421PGGLRLGAPA431LTSRQFREDD441FRRVVDFIDE
451-500451GVNIGLEVKR461KTAKLQDFKS471FLLKDPETSQ481RLANLRQQVE491QFARGFPMPG
501-504501FDER
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
16 - - -
Deep-Palm: 0.97
21 - - -
Deep-Palm: 0.97
68 - - -
Deep-Palm: 0.93
80 -
MLE (39008777)
-
Deep-Palm: 0.98
91 SWISSPALM DBPTM CYSMODDB Serine hydroxymethyltransferase
liver (26165157)
MLE (39008777)
-
GPS-Palm: 0.92
Deep-Palm: 0.96
119 - - -
Deep-Palm: 0.96
241 - - -
Deep-Palm: 0.90
343 - - -
Deep-Palm: 0.84
412 - - -
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Liver
Specificity: 0.667
4/4 (100.0%)
2
Testis
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine