Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9D110 Mthfs 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate … Mus musculus (Mouse) 203 aa

Protein Details: Q9D110 (Mthfs)

Protein Information
AccessionQ9D110
Protein Names5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)
Gene SymbolMthfs
OrganismMus musculus (Mouse)
Length203 aa
IsoformsNo isoforms
Related PMIDs 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAVTVNSAK11RGLRAELKQR21LRALSAEERL31RQSLLLTQKV41IAHNQYQNSK
51-10051RISIFLSMQD61EVETEVIIKD71IFKQGKICFI81PRYQFQSNHM91DMVRLTSSEE
101-150101IALLPKTSWN111IHQPGEGDVR121EEALSTGGLD131LIFLPGLGFD141KDGNRLGRGK
151-200151GYYDTYLKRC161VQHQEVKPYT171MALAFKEQIC181PQIPVDEHDM191KVDEVLYEDS
201-203201PAS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
78 - - -
Deep-Palm: 0.12
160 - - -
Deep-Palm: 0.78
180 - - -
Deep-Palm: 0.31
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Liver
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine