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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9D710 Tmx2 Thioredoxin-related transmembrane protein 2 (Thioredoxin … Mus musculus (Mouse) 295 aa

Protein Details: Q9D710 (Tmx2)

Protein Information
AccessionQ9D710
Protein NamesThioredoxin-related transmembrane protein 2 (Thioredoxin domain-containing protein 14)
Gene SymbolTmx2
OrganismMus musculus (Mouse)
Length295 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAVLAPLIAL11VYSVPRLSRW21LARPYCLLSA31LLSIAFLLVR41KLPPICNGLP
51-10051TQREDGNPCD61FDWREVEILM71FLSAIVMMKN81RRSITVEQHV91GNIFMFSKVA
101-150101NAILFFRLDI111RMGLLYLTLC121IVFLMTCKPP131LYMGPEYIKY141FNDKTIDEEL
151-200151ERDKRVTWIV161EFFANWSNDC171QSFAPIYADL181SLKYNCSGLN191FGKVDVGRYT
201-250201DVSTRYKVST211SPLTRQLPTL221ILFQGGKEVI231RRPQIDKKGR241AVSWTFSEEN
251-295251VIREFNLNEL261YQRAKKHSKG271GDMSEEKPVD281PAPTTVPDGE291NKKDK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
26 - - -
Deep-Palm: 0.98
46 - -
Brain (31311849)
GPS-Palm: 0.94
Deep-Palm: 0.96
59 - -
Brain (35358180)
Deep-Palm: 0.28
120 - - -
Deep-Palm: 0.59
127 - - -
Deep-Palm: 0.43
170 - - -
Deep-Palm: 0.07
186 SWISSPALM DBPTM CYSMODDB Thioredoxin
Liver (28526873)
-
GPS-Palm: 0.93
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.357
5/5 (100.0%)
2
Testis
Specificity: 0.143
2/2 (100.0%)
1
Brain
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.429
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine