Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9D7G0 Prps1 Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) … Mus musculus (Mouse) 318 aa

Protein Details: Q9D7G0 (Prps1)

Protein Information
AccessionQ9D7G0
Protein NamesRibose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)
Gene SymbolPrps1
OrganismMus musculus (Mouse)
Length318 aa
IsoformsNo isoforms
Related PMIDs 28526873 29217618 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPNIKIFSGS11SHQDLSQKIA21DRLGLELGKV31VTKKFSNQET41CVEIGESVRG
51-10051EDVYIVQSGC61GEINDNLMEL71LIMINACKIA81SASRVTAVIP91CFPYARQDKK
101-150101DKSRAPISAK111LVANMLSVAG121ADHIITMDLH131ASQIQGFFDI141PVDNLYAEPA
151-200151VLKWIRENIS161EWRNCTIVSP171DAGGAKRVTS181IADRLNVDFA191LIHKERKKAN
201-250201EVDRMVLVGD211VKDRVAILVD221DMADTCGTIC231HAADKLLSAG241ATRVYAILTH
251-300251GIFSGPAISR261INNACFEAVV271VTNTIPQEDK281MKHCSKIQVI291DISMILAEAI
301-318301RRTHNGESVS311YLFSHVPL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 Phosphoribosyltransferase-like Ribose-phosphate pyrophosphokinase Ribose-phosphate pyrophosphokinase, N-terminal domain Pribosyltran N 2 -
Brain (35358180)
Deep-Palm: 0.96
60 - - -
Deep-Palm: 0.95
77 - - -
Deep-Palm: 0.79
91 SWISSPALM DBPTM CYSMODDB N-terminal domain of ribose phosphate pyrophosphokinase
Liver (28526873)
Brain (31311849)
GPS-Palm: 0.95
Deep-Palm: 0.95
165 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.90
Deep-Palm: 0.89
226 - -
Brain (35358180)
Deep-Palm: 0.93
230 - -
Brain (35358180)
Deep-Palm: 0.92
265 - -
Brain (35358180)
Deep-Palm: 0.93
284 - - -
Deep-Palm: 0.81
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.194
6/6 (100.0%)
4
Brain
Specificity: 0.129
4/4 (100.0%)
1
Raw 264.7
Specificity: 0.032
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
20
Brain tissue (Mass)
Specificity: 0.645
20/56 (35.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine