Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9D819 Ppa1 Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate … Mus musculus (Mouse) 289 aa

Protein Details: Q9D819 (Ppa1)

Protein Information
AccessionQ9D819
Protein NamesInorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)
Gene SymbolPpa1
OrganismMus musculus (Mouse)
Length289 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGFSSEERA11APFTLEYRVF21LKNEKGQYIS31PFHDVPIYAD41KDVFHMVVEV
51-10051PRWSNAKMEI61ATKDPLNPIK71QDVKKGKLRY81VANLFPYKGY91IWNYGAIPQT
101-150101WEDPGHSDKH111TGCCGDNDPI121DVCEIGSKVC131ARGEIIRVKV141LGILAMIDEG
151-200151ETDWKVIAIN161VDDPDAANYK171DISDVERLKP181GYLEATVDWF191RRYKVPDGKP
201-250201ENEFAFNAEF211KNKDFAVDII221KSTHDYWKAL231VTKKTDGKGI241SCMNTTVSES
251-289251PFKCDPDAAK261AIVDALPPPC271ESACSLPTDV281DKWFHQQKN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
113 - -
Brain (35358180)
Deep-Palm: 0.06
114 - -
Brain (35358180)
Deep-Palm: 0.06
123 - -
Brain (35358180)
Deep-Palm: 0.16
130 - - -
GPS-Palm: 0.89
Deep-Palm: 0.77
242 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.83
254 - - -
Deep-Palm: 0.49
270 -
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.94
274 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.71
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.167
5/5 (100.0%)
3
Brain
Specificity: 0.100
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.909
20
Brain tissue (Mass)
Specificity: 0.667
20/56 (35.7%)
2
Liver tissue (Mass)
Specificity: 0.067
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine