Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9D892 Itpa Inosine triphosphate pyrophosphatase (ITPase) (Inosine … Mus musculus (Mouse) 198 aa

Protein Details: Q9D892 (Itpa)

Protein Information
AccessionQ9D892
Protein NamesInosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.66) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) (XTP/dITP diphosphatase)
Gene SymbolItpa
OrganismMus musculus (Mouse)
Length198 aa
IsoformsNo isoforms
Related PMIDs 29733200 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAASLVGKKI11VFVTGNAKKL21EEVIQILGDN31FPCTLEAQKI41DLPEYQGEPD
51-10051EISIQKCREA61ARQVQGPVLV71EDTCLCFNAL81GGLPGPYIKW91FLQKLKPEGL
101-150101HQLLAGFEDK111SAYALCTFAL121STGDPSQPVL131LFRGQTSGQI141VMPRGSRDFG
151-198151WDPCFQPDGY161EQTYAEMPKS171EKNTISHRFR181ALHKLQEYFS191VAAGAGDH
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
33 Inosine triphosphate pyrophosphatase-like RdgB/HAM1 -
Brain (35358180)
Deep-Palm: 0.94
57 - - -
Deep-Palm: 0.94
74 - - -
Deep-Palm: 0.98
76 - - -
Deep-Palm: 0.97
116 - -
Brain (35358180)
Deep-Palm: 0.92
154 SWISSPALM DBPTM CYSMODDB Ham1 family
Forebrain (28680068)
Brain (35358180)
Deep-Palm: 0.22
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
Testis
Specificity: 0.087
2/2 (100.0%)
2
Liver
Specificity: 0.087
2/2 (100.0%)
1
Brain
Specificity: 0.043
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.783
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine