Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9D8T2 Gsdmd Gasdermin-D (Gasdermin domain-containing protein 1) … Mus musculus (Mouse) 487 aa

Protein Details: Q9D8T2 (Gsdmd)

Protein Information
AccessionQ9D8T2
Protein NamesGasdermin-D (Gasdermin domain-containing protein 1) [Cleaved into: Gasdermin-D, N-terminal (GSDMD-NT) (mGSDMD-NTD) (p30); Gasdermin-D, C-terminal (GSDMD-CT) (mGSDMD-CTD) (p20); Gasdermin-D, p13 (Gasdermin-D, 13 kDa) (13 kDa GSDMD); Gasdermin-D, p40]
Gene SymbolGsdmd
OrganismMus musculus (Mouse)
Length487 aa
IsoformsNo isoforms
Related PMIDs 34884899 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPSAFEKVVK11NVIKEVSGSR21GDLIPVDSLR31NSTSFRPYCL41LNRKFSSSRF
51-10051WKPRYSCVNL61SIKDILEPSA71PEPEPECFGS81FKVSDVVDGN91IQGRVMLSGM
101-150101GEGKISGGAA111VSDSSSASMN121VCILRVTQKT131WETMQHERHL141QQPENKILQQ
151-200151LRSRGDDLFV161VTEVLQTKEE171VQITEVHSQE181GSGQFTLPGA191LCLKGEGKGH
201-250201QSRKKMVTIP211AGSILAFRVA221QLLIGSKWDI231LLVSDEKQRT241FEPSSGDRKA
251-300251VGQRHHGLNV261LAALCSIGKQ271LSLLSDGIDE281EELIEAADFQ291GLYAEVKACS
301-350301SELESLEMEL311RQQILVNIGK321ILQDQPSMEA331LEASLGQGLC341SGGQVEPLDG
351-400351PAGCILECLV361LDSGELVPEL371AAPIFYLLGA381LAVLSETQQQ391LLAKALETTV
401-450401LSKQLELVKH411VLEQSTPWQE421QSSVSLPTVL431LGDCWDEKNP441TWVLLEECGL
451-487451RLQVESPQVH461WEPTSLIPTS471ALYASLFLLS481SLGQKPC
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
39 Gasdermin Gasdermin, pore forming domain - -
Deep-Palm: 0.84
57 - - -
Deep-Palm: 0.79
77 - - -
Deep-Palm: 0.69
122 - - -
Deep-Palm: 0.77
192 SWISSPALM Gasdermin pore forming domain - -
Deep-Palm: 0.96
265 - - -
Deep-Palm: 0.96
299 - - -
Deep-Palm: 0.94
340 - - -
Deep-Palm: 0.97
354 - - -
Deep-Palm: 0.97
358 - - -
Deep-Palm: 0.98
434 - - -
Deep-Palm: 0.91
448 - - -
Deep-Palm: 0.61
487 - - -
GPS-Palm: 0.97
Deep-Palm: 0.04
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine