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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9DBC7 Prkar1a cAMP-dependent protein kinase type I-alpha … Mus musculus (Mouse) 381 aa

Protein Details: Q9DBC7 (Prkar1a)

Protein Information
AccessionQ9DBC7
Protein NamescAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]
Gene SymbolPrkar1a
OrganismMus musculus (Mouse)
Length381 aa
IsoformsNo isoforms
Related PMIDs 29733200 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MASGSMATSE11EERSLRECEL21YVQKHNIQAL31LKDSIVQLCT41TRPERPMAFL
51-10051REYFERLEKE61EARQIQCLQK71TGIRTDSRED81EISPPPPNPV91VKGRRRRGAI
101-150101SAEVYTEEDA111ASYVRKVIPK121DYKTMAALAK131AIEKNVLFSH141LDDNERSDIF
151-200151DAMFPVSFIA161GETVIQQGDE171GDNFYVIDQG181EMDVYVNNEW191ATSVGEGGSF
201-250201GELALIYGTP211RAATVKAKTN221VKLWGIDRDS231YRRILMGSTL241RKRKMYEEFL
251-300251SKVSILESLD261KWERLTVADA271LEPVQFEDGQ281KIVVQGEPGD291EFFIILEGTA
301-350301AVLQRRSENE311EFVEVGRLGP321SDYFGEIALL331MNRPRAATVV341ARGPLKCVKL
351-381351DRPRFERVLG361PCSDILKRNI371QQYNSFVSLS381V
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
18 Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit - -
Deep-Palm: 0.95
39 Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain - -
GPS-Palm: 0.90
Deep-Palm: 0.88
67 -
brain (39008777)
MLE (39008777)
-
Deep-Palm: 0.94
347 - - -
Deep-Palm: 0.98
362 SWISSPALM DBPTM CYSMODDB -
liver (26165157)
MLE (39008777)
-
GPS-Palm: 0.91
Deep-Palm: 0.95
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Liver
Specificity: 0.750
3/3 (100.0%)
1
Brain
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine