Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q9DBG1 Cyp27a1 Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) … Mus musculus (Mouse) 533 aa

Protein Details: Q9DBG1 (Cyp27a1)

Protein Information
AccessionQ9DBG1
Protein NamesSterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)
Gene SymbolCyp27a1
OrganismMus musculus (Mouse)
Length533 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAWSRTRLR11WTLLDPRVVG21RGLCPQGARA31KATIPAALQA41QESTEGPGTG
51-10051QDRPRLRSPA61ELPGTGTLQF71LFQLFLQGYV81LHLPDLQVLN91KTKYGPMWTT
101-150101SFGTYTNVNL111ASAPLLEQVM121RQEGKYPIRD131HMDQWKDHRD141HKGLTYGIFI
151-200151AQGEQWYHLR161QALKQRLLKP171DEAALYTDAL181NEVISDFITR191LDQVRAESES
201-250201GDQVPDMAHL211LYHLALEAIT221YILFEKRIGC231LKPSIPEDTA241AFIRSVAIMF
251-300251QNSVYITFLP261KWTRPLLPFW271KRYLNGWDNI281FSFGKKLIDE291KVQELKAQLQ
301-350301ETGPDGVRVS311GYLHFLLTNE321LLSTQETIGT331FPELLLAGVD341TTSNTLTWAL
351-400351YHLSKSPEIQ361EALHKEVTGV371VPFGKVPQHK381DFAHMPLLKA391VIKETLRLYP
401-450401VVPTNSRIIT411EKETEINGFL421FPKNTQFVLC431HYVVSRDPSV441FPEPNSFQPH
451-500451RWLRKKEADN461PGILHPFGSV471PFGYGVRSCL481GRRIAELEMQ491LMLSRLVQKY
501-533501EIALAPGMGE511VKTVSRIVLV521PSKKVRLHFL531QRQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
24 - - -
GPS-Palm: 0.90
Deep-Palm: 0.98
230 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
liver (26165157)
-
GPS-Palm: 0.93
Deep-Palm: 0.94
430 SWISSPALM DBPTM CYSMODDB Cytochrome P450
liver (26165157)
Liver (28526873)
-
Deep-Palm: 0.90
479 - - -
GPS-Palm: 0.93
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
6
Liver
Specificity: 0.857
6/6 (100.0%)
1
Testis
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine